What's New in ADME & DDI

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New resources to help you understand the drug interaction risks and ADME characteristics of your therapeutic.

This week's Fierce Biotech is brought to you by BioIVT.
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2024 ISSX Posters Now Available The posters that BioIVT presented at this year's ISSX Meeting, "An Evaluation of CYP and Non-CYP Reaction Phenotyping Study Trends from 2000-2023" and "Monocarboxylate Transporters 8 and 10: Siblings with Different Personalities," are now available to download. View Posters

Tiered ADME Study Options: Tailored to Fit Specific Goals Learn about the tiered options that BioIVT offers for many drug-drug interaction and drug metabolism studies, including the differences between the tiers and which would be most appropriate for your specific goals and stage of development. Read More

Assessing the Research Value of Biospecimens for ADC Development with Ki67 Tissue Staining Ki67 staining is indispensable for validating tissue blocks, offering essential insights into cell proliferation, tumor heterogeneity, target validation, biomarker correlation, therapeutic efficacy, QC and standardization. Read More

Safety Considerations for the Development of Antibody-drug Conjugates (ADCs) This article provides an industry overview from the perspective of drug safety, including a discussion of approved ADCs as well as drug interaction guidance, cases and strategies for in vitro evaluation. Read More

Thawing & Plating Cryoplateable Hepatocytes Proper thawing and plating is critical to ensuring your data is as accurate as possible. Take a look at this instructional video for useful information and tips to maximize the performance of your cells. Watch Now

Micropatterned Primary Hepatocyte Co-culture for Liver Disease Modeling & Drug Screening Researchers have been using BioIVT's HEPATOPAC as a long-term functional in vitro model for compound screening, toxicity evaluation and assessment of gene regulation. View Research

DTCs in Cancer Research: Benefits and Considerations Dissociated tumor cells (DTCs) offer significant advantages in in vitro drug screening and evaluation, personalized medicine applications, and modeling tumor heterogeneity. However, ethical considerations in sourcing starting materials and the limitations of DTCs must be carefully managed. View Research

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What's New in ADME & DDI

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