This pain killer can make emergency contraception more effective

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Taking a pain killer can make emergency contraception more effective

By Alice Park Senior Health Correspondent

It’s not a combination that seems to make sense at first—an anti-inflammatory pain killer and an emergency contraceptive pill. But researchers report that taking a single 40 mg pill of piroxicam, an anti-inflammatory drug that’s available by prescription only, with the morning-after pill levonorgestrel can prevent pregnancy better than levonorgestrel alone.

Here’s what the study authors, based in Hong Kong and Sweden, found in study results published yesterday:

Combining piroxicam with levonorgestrel prevented 94.7% of expected pregnancies, compared to 63.4% of expected pregnancies prevented among women getting levonorgestrel and a placebo. Piroxicam belongs to a class of drugs known as COX inhibitors, which, like levonorgestrel, work on prostaglandins to inhibit ovulation, the first step to pregnancy. The researchers support adding piroxicam to emergency contraception to further reduce pregnancy, but it’s up to regulators to greenlight the combination.

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Today's newsletter was written by Alice Park and Oliver Staley, and edited by Angela Haupt.

This pain killer can make emergency contraception more effective

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