Up to 10 million key workers and those in their households are now eligible to book a coronavirus test online, or through their employer. All workers deemed essential in England can register for tests on the government's website, if they or a family member have virus symptoms. The move was announced by Health Secretary Matt Hancock, who is under pressure to meet his own target of carrying out 100,000 tests a day by the end of this month, with the latest testing figures shy of a quarter of the way there.  

With some 616 people having died with the virus in UK hospitals in the last 24-hour reported period, bringing the total to 18,738, Europe's first human trial of a Covid-19 vaccine is under way in Oxford. We spoke to the first of 800 volunteers given jabs. However, a workable vaccine remains some way off, as our health correspondent James Gallagher explains.

Meanwhile, lockdown rules in Wales are being tightened to clamp down on the use of second homes and discourage people from exercising outside their local area. And a Royal Navy captain has been sent home on leave, after the crew of a nuclear-powered submarine was filmed having a party during the coronavirus lockdown.

Donald Trump has been criticised by the medical community over a "dangerous" and "ridiculous" suggestion that coronavirus might be treated by injecting disinfectant into the body. The US president also appeared to propose irradiating patients' bodies with UV light, an idea dismissed by a doctor at his daily briefing.  Meanwhile, hopes for a new antiviral drug, remdesivir, were dashed when it failed in its first randomised clinical trial, according to draft documents accidentally published by the World Health Organization. The US firm behind the drug says the draft mischaracterises the Chinese study.

With much of Europe still locked down, psychologists warn that nations must prepare for a mental health crisis. Our Europe Correspondent Jean Mackenzie brings an emotional report from a Red Cross psychological support centre, where staff say they are overwhelmed by the number of calls. Our live page has the latest global developments, including a summary of the different approaches taken by countries to restrictions during Islam's holy month of Ramadan. Health reporter Rachel Schraer examines how best to look after your immune system while fasting.

Light relief came from stars of shows such as Doctor Who, The Vicar of Dibley and Miranda, who sent messages of hope via Thursday evening's BBC One charity special The Big Night In. The event raised more than £27m for causes supported by Children in Need and Comic Relief. Catch up on the highlights. Meanwhile, sculptor Sir Antony Gormley is among artists to have been responding to the pandemic. See some of their work.

It's payday for many Britons, but a large proportion will earn less this month than usual. We explain what help is available. We meet a TV retail analyst who took a job on a supermarket shop floor after being laid off from his job in the city. And, for our regular My Money blog series, auditor Claire Millington describes a week of paying hefty bills   - including for childcare she no longer has access to - but recouping a little as a result of restrictions on movement.

On the World Service, Witness History explores the development of the Brompton Manley Ventilator - a precursor to many of the machines proving essential in the treatment of the worst symptoms of Covid-19 - by a gifted anaesthetist at a London hospital. Meanwhile, the latest  Ouch podcast examines the difficulty of lip-reading when everyone's wearing face masks.

Some front pages report cabinet disunity over the extent to which the UK should remain locked down. Scotland's First Minister Nicola Sturgeon's publication of a 26-page framework for easing the lockdown has heaped pressure on UK ministers to do the same, according to the Times. Concerns among some in the cabinet that the lockdown has gone "too far" will prompt Prime Minister Boris Johnson to return to his desk on Monday, says the Daily Telegraph. The Daily Express quotes Health Secretary Matt Hancock saying opening coronavirus testing to millions more workers will "get Britain back on her feet". The Daily Mail describes the move as being part of a "frantic" final push by Mr Hancock to hit his 100,000-tests-a-day target by the month's end. Meanwhile, the Metro leads on the "clappin' fantastic" efforts of Theo Woods, 13, who applauded continuously for 12 hours to raise money for the NHS. Read the full review.

From elsewhere

There's nothing like some animal magic to provide a little cheer. So, meet Prickles the sheep - and find out how she spent seven years on the run in Australia. A less happy tale is one of Hong Kong's pink dolphins, who now number just 32. But some are fighting to save them. And it's Friday, which means it's time to take on our quiz of the week's news.