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COVID-19 mixed with flu increases risk of severe illness and death Posted: 25 Mar 2022 07:06 PM PDT Adults in hospital who have COVID-19 and the flu at the same time are at much greater risk of severe disease and death compared with patients who have COVID-19 alone or with other viruses, research shows. |
New study reveals why HIV remains in human tissue even after antiretroviral therapy Posted: 25 Mar 2022 03:59 PM PDT Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system. Now, new research by University of Alberta immunologist Shokrollah Elahi reveals a possible answer to the mystery of why infected people can't get rid of HIV altogether. Elahi and his team found that in HIV patients, killer T cells -- a type of white blood cells responsible for identifying and destroying cells infected with viruses -- have very little to none of a protein called CD73. Because CD73 is responsible for migration and cell movement into the tissue, the lack of the protein compromises the ability of killer T cells to find and eliminate HIV-infected cells, explained Elahi. |
Alpaca nanobodies potently neutralize SARS-CoV-2 variants Posted: 25 Mar 2022 03:59 PM PDT Researchers have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants. The approach led to the discovery of multiple nanobodies that in cell cultures and mice effectively blocked infection with different SARS-CoV-2 variants. The findings could pave the way for new treatments against COVID-19. |
Attention to objects in peripheral vision is not driven by tiny eye movements Posted: 25 Mar 2022 03:59 PM PDT New research shows that while microsaccades seem to boost or diminish the strength of the brain signals underlying attention, eye movements are not drivers of those brain signals. |
Design of protein binders from target structure alone Posted: 25 Mar 2022 03:58 PM PDT Scientists have now created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses. This solves a long-standing challenge in drug development and may lead to new treatments for cancer, diabetes, infection, inflammation, and beyond. |
New pathway for DNA transfer discovered in tumor microenvironment Posted: 25 Mar 2022 03:58 PM PDT Researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread. |
COVID-19 infection linked to higher risk of neuropathy Posted: 25 Mar 2022 09:26 AM PDT Researchers have found that many people who tested positive for the coronavirus in the early months of the pandemic also experienced peripheral neuropathy -- pain, tingling and numbness in the hands and feet -- during and following their bouts with COVID-19. |
How fingers could point to a link between low testosterone and COVID hospitalizations Posted: 25 Mar 2022 09:26 AM PDT Could the length of a person's fingers provide a clue to how ill they might get after contracting COVID-19? |
Reduced kidney function increases bleeding risk in antithrombotic therapy Posted: 25 Mar 2022 06:39 AM PDT While kidney function is known to be related to bleeding event risk, researchers conducted a post-hoc subgroup analysis of the Atrial Fibrillation and Ischemic Events with Rivaroxaban in Patients with Stable Coronary Artery Disease (AFIRE) trial to determine the impact of kidney function on the risk of recurrent bleeding events during antithrombotic therapy. Their analysis revealed that the effect of kidney function on recurrent bleeding risk events was quite large for patients undergoing this treatment. |
Liver disease increases as result of life-style changes due to COVID-19, study reveals Posted: 25 Mar 2022 06:39 AM PDT In a retrospective study drawing data from 973 participants between 2018 and 2020, researchers find that cases of metabolic dysfunction-associated fatty liver disease (MAFLD) increased from 22 pre-pandemic to 44 mid-pandemic. Additionally, univariate and multivariate analysis of lifestyle habits reveal late-night meals pre-pandemic and increased alcohol intake mid-pandemic as independent lifestyle predictors of developing the disease. |
Scientists identify overgrowth of key brain structure in babies who later develop autism Posted: 25 Mar 2022 06:38 AM PDT New research demonstrates overgrowth of the amygdala in the first year of life, before babies show most of the behavioral symptoms that later consolidate into a diagnosis of autism. This overgrowth may be unique to autism, as babies with fragile X syndrome show a different brain growth pattern. |
Once called cellular debris, tiny bubbles may play key role in understanding, treating diseases Posted: 24 Mar 2022 03:46 PM PDT Scientists have long puzzled about a critical way that cells communicate with one another, but researchers have now used a simple roundworm to solve the mystery. |
Aspirin may reduce death in hospitalized COVID-19 patients, study finds Posted: 24 Mar 2022 09:25 AM PDT Researchers found that early aspirin treatment helped reduce mortality in patients with moderate COVID, especially for the elderly and those with comorbidities. |
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