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ScienceDaily: Top Health News |
Does strep throat lead to the development of tics? Posted: 02 Feb 2022 01:27 PM PST A new study has found no link between a strep throat infection and the development of tics in children who have a parent or sibling with a chronic tic disorder. |
ADHD medicine may treat symptoms of genetic movement disorder in children, study finds Posted: 02 Feb 2022 12:39 PM PST Using a common attention deficit hyperactivity disorder (ADHD) medication appears to help manage the symptoms of a rare and currently difficult to treat genetic movement disorder primarily found in children, according to a new study. The disorder, KCNMA1-linked channelopathy, named after the affected gene, can cause abnormal, involuntary movements from collapsing episodes, in which patients slump forward with their arms and legs appearing rigid. |
Quick COVID breathalyzer could allow mass screening in public places Posted: 02 Feb 2022 11:31 AM PST Researchers have developed a prototype 'breathalyzer' that can sensitively and accurately diagnose COVID-19, even in asymptomatic individuals, in less than 5 minutes. |
Anxiety and neuroticism linked to ability to experience ASMR Posted: 02 Feb 2022 11:30 AM PST A study has uncovered new evidence linking higher levels of neuroticism and anxiety with the ability to experience a deeply relaxing sensation known as the Autonomous Sensory Meridian Response (ASMR). |
Engineers develop surgical 'duct tape' as an alternative to sutures Posted: 02 Feb 2022 11:30 AM PST Engineers have developed a kind of surgical 'duct tape.' The strong, flexible, and biocompatible sticky patch can be applied to biological tissues and organs to help seal tears and wounds. |
Testing the effectiveness of KN95 and surgical mask 'fit hacks' Posted: 02 Feb 2022 11:30 AM PST Researchers have tested a variety of popular hacks for improving the fit of KN95 and surgical masks, and found that while some hacks do improve fit, they can also come at the cost of the wearer's comfort. |
The key to a powerful antibiotic's formation now clear Posted: 02 Feb 2022 10:47 AM PST According to new research, the enzyme tokK helps synthesize a chain of methyl groups that allows potent antibiotics called carbapenems to circumvent antibiotic resistance. |
Living in a walkable neighborhood lowers risk of excessive weight gain during pregnancy Posted: 02 Feb 2022 10:47 AM PST In one of the first studies to examine the link between neighborhood characteristics and weight gain during pregnancy, researchers find that pregnant people who live in walkable neighborhoods in New York City have lower odds of excessive gestational weight gain (GWG) than those who live elsewhere in the city. They also found that living in a neighborhood with high rates of poverty increased the odds of excessive GWG. |
Minimizing long-term lung damage in COVID patients Posted: 02 Feb 2022 10:46 AM PST A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae -- chronic complications resulting from COVID-19 infection, according to a new review article. |
Mechanism revealed behind loss of smell with COVID-19 Posted: 02 Feb 2022 09:43 AM PST Researchers have discovered a mechanism that may explain why COVID-19 patients lose their sense of smell, as well as having implications for long COVID. |
Simple, inexpensive, fast and accurate nano-sensors pinpoint infectious diseases Posted: 02 Feb 2022 08:18 AM PST Researchers describe a novel method for detecting viruses like Ebola virus (EBOV) and SARS CoV-2. |
Untangling a DNA replication mystery may lead to new antimalarial drugs Posted: 02 Feb 2022 08:18 AM PST The function of an enzyme, critical to most forms of life, has been revealed. |
Predicting cell fates: Researchers develop AI solutions for next-gen biomedical research Posted: 02 Feb 2022 08:18 AM PST Data is not only the answer to numerous questions in the business world; the same applies to biomedical research. In order to develop new therapies or prevention strategies for diseases, scientists need more and better data, faster and faster. However, the quality is often very variable and the integration of different data sets often almost impossible. |
Cancer treatment: A berry from Brazil helps out Posted: 02 Feb 2022 08:18 AM PST Castalagin, a polyphenol from the Amazonian fruit camu-camu, increases the efficacy of immunotherapy in mice by modifying their microbiome, researchers find. |
Genome study finds unexpected variation in a fundamental RNA gene Posted: 02 Feb 2022 08:17 AM PST A genome study to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist. |
Posted: 02 Feb 2022 08:17 AM PST Using cellphone mobility data and COVID-19 hospital admissions data, researchers have reliably forecast regional hospital demands for almost two years, according to a new study. The forecasting system, which municipal authorities credit with helping Austin maintain the lowest COVID-19 death rate among all large Texas cities, has been built out for use by 22 municipal areas in Texas and can be used by any city to guide COVID-19 responses as the virus continues to spread. |
Posted: 02 Feb 2022 08:17 AM PST Researchers have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models, providing new clues to the disease and giving researchers a powerful new tool to test new therapies. |
Different autism risk genes, same effects on brain development Posted: 02 Feb 2022 08:17 AM PST Researchers have found that three different autism risk genes actually affect similar aspects of neuron development and the same neuron types, although each gene acted through unique molecular mechanisms. Additionally, a person's specific genomic background fine-tuned the genes' effects. The study was conducted using miniature 3D models, or 'organoids,' of the human cerebral cortex, the part of the brain responsible for cognition, perception, and language. The results advance our understanding of autism spectrum disorder and are a first step toward finding treatments for the condition. |
3D structure of regulator protein revealed Posted: 02 Feb 2022 06:19 AM PST A team of researchers has revealed the structure of a protein complex which is an important regulator of cellular degradation processes. |
Research advances technology of AI assistance for anesthesiologists Posted: 02 Feb 2022 06:19 AM PST A new deep learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general anesthesia could aid anesthesiologists and augment monitoring, according to a new study. |
Immunological memory provides long-term protection against coronavirus Posted: 02 Feb 2022 05:03 AM PST Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of COVID-19. Researchers have now discovered how these memory T cells form. |
Magnetic seeds used to heat and kill cancer Posted: 01 Feb 2022 05:11 PM PST Scientists have developed a novel cancer therapy that uses an MRI scanner to guide a magnetic seed through the brain to heat and destroy tumors. |
Paternal alcohol use increases frequency of fetal development issues Posted: 01 Feb 2022 01:10 PM PST Prenatal visits have traditionally focused almost exclusively on the behavior of mothers, but new research continues to suggest that science should be looking more closely at the fathers' behavior as well. |
People in urban areas had better access to care and lower copays than rural areas Posted: 01 Feb 2022 11:40 AM PST Substance abuse, access to mental health care and costs remain a burden for people living in rural areas, even if they have private insurance. |
Study finds higher risk in families of Black patients with inherited heart muscle disease Posted: 01 Feb 2022 11:40 AM PST Black patients diagnosed with dilated cardiomyopathy (DCM) of unknown cause are more likely to have family members at risk of developing the heart muscle disease than families of white patients, according to results of a multi-site study. |
The U.S. is failing to care for traumatic brain injury survivors, experts say Posted: 01 Feb 2022 11:40 AM PST The United States care system is often failing to meet the needs of individuals, families and communities affected by traumatic brain injury, according to a report from the National Academies of Sciences, Engineering, and Medicine. The authors make many recommendations for advancing progress in TBI care, including changes to classification methods, improving research funding and establishing continuity of care. |
New model to investigate fibrosis treatments without use of animals Posted: 01 Feb 2022 11:40 AM PST A new 3D connective tissue model gives researchers a sophisticated tool to understand the underlying mechanisms of connective tissue disorders and test potential treatments. |
Scientists unveil promising new approach to diabetes prevention Posted: 01 Feb 2022 11:40 AM PST A team of scientists has conducted promising early tests of a new strategy that might one day be used to prevent or treat type 2 diabetes. The scientists tested an experimental compound called IXA4 in obese mice. They showed that the compound activates a natural signaling pathway that protects the animals from harmful, obesity-driven metabolic changes that would normally lead to diabetes. |
How Omicron escapes from antibodies Posted: 01 Feb 2022 11:39 AM PST Dozens of mutations in the spike protein of the Omicron variant help it to evade all four of the classes of antibodies that can target SARS-CoV-2, according to a new study. This includes antibodies generated by the immune systems of vaccinated or previously infected people, as well as most of the monoclonal antibody treatments that have been developed. |
Researchers develop highly accurate modeling tool to predict COVID-19 risk Posted: 01 Feb 2022 11:39 AM PST Researchers have combined location density with real-world mobility data to predict the risk of infection from COVID-19 at specific locations with unprecedented accuracy. |
Picture warnings on sodas? A promising tool to fight childhood obesity Posted: 01 Feb 2022 11:39 AM PST The first study in a laboratory 'mini mart' shows picture warnings reduced parental purchases of sugary drinks like juice and soda. Researchers say the warning labels could be new tool in fighting childhood obesity. |
Obesity may increase risk of some female reproductive disorders Posted: 01 Feb 2022 11:39 AM PST Obesity is associated with an increased risk of developing female reproductive disorders, however, the roles and mechanisms of obesity in the cause(s) of reproductive conditions are unclear. A study suggests an etiological link between obesity and a range of female reproductive conditions, but the extent of this link differs among conditions. |
Single-use sensor strips detect cerebrospinal fluid leaks Posted: 01 Feb 2022 08:53 AM PST Researchers developed a single-use sensor strip that can be used with a circuit board to detect cerebrospinal fluid leaks. They collected nine clinical samples and introduced the test fluid into a small liquid channel on the tip of the sensor strips. The liquid channel held electrodes, which contained antibodies specific to proteins found only in human cerebrospinal fluid. The circuit board analyzed the signal and produced a four-digit number that correlates to the concentration of the protein beta-2-transferrin, found in CSF. |
More predictive in vitro assays may improve nanomedicine Posted: 01 Feb 2022 08:52 AM PST One recent obstacle to drug delivery research is an observed weak correlation between in vitro and in vivo performance. When nanoparticles are applied intravenously, they face several obstacles that differ from in vitro situations. Nanoparticles are usually covered by a biomolecular multilayer (a protein corona), which alters the physiochemical properties, pharmacokinetics, and toxicity profile of the nanoparticles. |
Posted: 01 Feb 2022 08:52 AM PST First generation COVID-19 vaccines have been highly effective, but also have limitations. Now, scientists have developed a more targeted vaccine that, in animal studies, shows stronger, broader, and more durable protection in a single, low dose. |
Urgent investment needed in preventing deadly disease Posted: 01 Feb 2022 08:52 AM PST Researchers are calling for urgent investment in the prevention of a devastating emerging disease that kills tens of thousands of people each year. A global systematic review reports on the frequency of a range of serious complications and very high risk for death among patients with found non-typhoidal Salmonella invasive disease. |
Hepatitis E virus defies alcohol-based hand disinfectants Posted: 01 Feb 2022 08:52 AM PST The hepatitis E virus (HEV) can cause serious liver inflammation and is the most common cause of acute virus-mediated hepatitis worldwide. Infection can be prevented through appropriate hygiene measures. Scientists have investigated the effectiveness of various common hand disinfectants against HEV. They were able to show that most formulations do not completely inactivate the virus. |
On the spot drug delivery with light-controlled organic microswimmers Posted: 01 Feb 2022 08:52 AM PST Scientists have developed organic microparticles that can steer through biological fluids and dissolved blood in unprecedented ways. Even in very salty liquids, the microswimmers can be propelled forward at high speed by visible light, either individually or as a swarm. Additionally, they are partially biocompatible and can take up and release cargo on demand. The material properties are so ideal they could pave the way toward designing semi-autonomous microrobots applied in biomedicine. |
How fuel poverty 'gets under the skin' Posted: 01 Feb 2022 08:52 AM PST New research shows that fuel poverty makes people's physical and mental health worse. Researchers found that not being able to keep homes warm enough affects people's levels of life satisfaction. But they also found that it impacts people's physical health by causing higher levels of inflammation, measured by fibrinogen, a blood-based biomarker. |
First virus infection linked with infections later in life Posted: 01 Feb 2022 08:52 AM PST Asymptomatic viral infections in the first days and weeks of a baby's life are associated with an increased risk of respiratory infections later in life, research suggests. |
Posted: 01 Feb 2022 08:52 AM PST A method of producing vital chemical building blocks for use in the pharmaceutical and agrochemical industries mimics how plants manufacture them. |
Posted: 01 Feb 2022 08:51 AM PST A new study revealed a pathological brain activity that precedes the onset of Alzheimer's first symptoms by many years: increased activity in the hippocampus during anesthesia and sleep, resulting from failure in the mechanism that stabilizes the neural network. The researchers believe that the discovery of this abnormal activity during specific brain states may enable early diagnosis of Alzheimer's, eventually leading to a more effective treatment of a disease that still lacks effective therapies. |
Growth charts for the brain help to explain mental illness Posted: 01 Feb 2022 08:51 AM PST Researchers have developed a set of growth charts for the brain. These 'brain charts' provide reference models for brain development and ageing across the entire human lifespan, based on a very large data set. These models can be used to make personalized predictions for each individual relevant to many brain conditions, and therefore have a high clinical potential. The software tools and models are available online. |
Finding structure in the brain’s static Posted: 01 Feb 2022 08:51 AM PST Researchers found that a monkey's state of attentiveness may be encoded in the shapes and speeds of slow electrical waves that course over the surface of the brain. Like a surfer that avoids smooth water and favors more active waves, the brain uses faster, choppier waves to process information to which it is paying attention. By separating how the brain encodes its state of attention versus stimuli to which it is responding, scientists hope to understand sleep, anesthesia, attention, and disease better. |
Response to exercise is key to novel device therapy for the most common type of heart failure Posted: 01 Feb 2022 08:51 AM PST A new study suggests that some patients with HFpEF may benefit from a novel, minimally invasive cardiac implant device called an atrial shunt. The study also offers new insight into the role exercise plays in understanding, diagnosing and treating this type of heart failure. |
COVID-19 less severe in fully vaccinated, study finds Posted: 01 Feb 2022 08:51 AM PST The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study. |
New computational tool predicts cell fates and genetic perturbations Posted: 01 Feb 2022 08:51 AM PST Researchers have built a machine learning framework that can define the mathematical equations describing a cell's trajectory from one state to another, such as its development from a stem cell into one of several different types of mature cell. The framework, called dynamo, can also be used to figure out the underlying mechanisms -- the specific cocktail of gene activity -- driving changes in the cell. |
Study links lead in childhood well water to teen delinquency Posted: 01 Feb 2022 08:36 AM PST Exposure to lead in drinking water from private wells during early childhood is associated with an increased risk of being reported for delinquency during teenage years, according to a new study. Researchers found that children who get their water from private wells before age 6 have higher blood lead levels and also have a 21% higher risk of being reported for any delinquency after age 14. |
Treatment keeps alcoholic monkeys from drinking as much Posted: 01 Feb 2022 08:06 AM PST A hormone produced by the liver called fibroblast growth factor 21 (FGF21) suppresses alcohol consumption in primates, finds a new study. Vervet monkeys with a strong preference for ethanol that were given an FGF21 analogue consumed 50% less alcohol. The study also studied the brain circuits involved in mice and found that the protein, known to also reduce sugar intake, acts on different circuits to reduce alcohol and sugar consumption. |
Lifestyle more likely to affect a child’s BMI than the weight of their mother Posted: 01 Feb 2022 04:45 AM PST Researchers have found that a high Body Mass Index (BMI) of a mother before and during pregnancy is not a major cause of high BMI in their offspring -- indicating that childhood and teen obesity is more likely to be a result of lifestyle factors. |
Complex three-dimensional kidney tissue generated in the lab from the scratch Posted: 01 Feb 2022 04:45 AM PST Researchers have created a complex kidney tissue solely from mouse embryonic stem cells. These organoids could lead the way to better kidney research and, eventually, artificial kidneys for human transplant. |
Sweet pressure: Scientists discover link between high blood pressure and diabetes Posted: 01 Feb 2022 04:45 AM PST The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar) has finally been cracked by an international team. |
Human gut bacteria have 'sex' to share vitamin B12 Posted: 01 Feb 2022 04:45 AM PST Your gut bacteria need vitamin B12 just as much as you do. Though DNA is usually passed from parent to child, new research shows gut bacteria transfer genes through 'sex' in order to take their vitamins. |
Foamy cells inspire better way to predict heart attacks Posted: 31 Jan 2022 01:15 PM PST A heart attack or stroke can blindside people who thought they were at low risk. Now, research has found a new model that could improve how we assess heart disease. |
Posted: 31 Jan 2022 12:32 PM PST While COVID-19 disease significantly impacts many pregnant women, the rates of transmission from mother to baby in pregnancy are very low. A new study has demonstrated that ACE-2, the receptor that allows SARS-CoV-2 to enter cells, is found in lower levels in the placentas of women with COVID-19 in pregnancy compared to women with normal (COVID negative) pregnancies. |
Promising results of Phase 1 drug trial for HIV patients Posted: 31 Jan 2022 12:32 PM PST A Phase 1 clinical trial has demonstrated the safety and efficacy of a novel immunotherapy drug in the treatment of HIV. |
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