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As we develop, the brain connects lessons learned differently Posted: 15 Nov 2021 12:10 PM PST A new study of brain activity patterns in people doing a memory task finds that the way we make inferences -- finding hidden connections between different experiences -- changes dramatically as we age. The study's findings might one day lead to personalized learning strategies based on a person's cognitive and brain development. The researchers found that whereas adults build integrated memories with inferences already baked in, children and adolescents create separate memories that they later compare to make inferences on the fly. |
Nascent polypeptides stabilize ribosomes for uninterrupted translation Posted: 15 Nov 2021 12:10 PM PST Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists have uncovered a novel role of nascent protein chains in stabilizing translating ribosomes. They suggest that longer peptide sequences spanning the ribosomal exit tunnel and bulky amino acid residues in the tunnel entry help stabilize the ribosome by bridging its subunits, ensuring uninterrupted translation. |
Researchers discover new insights about tau proteins in people living with ALS Posted: 15 Nov 2021 09:35 AM PST Investigators found elevated levels of tau and a phosphorylated form of the tau protein in brain tissue from deceased people who had amyotrophic lateral sclerosis (ALS) and carried a mutation in the C9orf72 gene. The team also identified new genetic mutations in the tau gene that may exacerbate ALS onset or progression. Tau in the cerebrospinal fluid may be a viable biomarker for ALS because levels correlate with disease progression. |
Researchers train computers to predict the next designer drugs Posted: 15 Nov 2021 09:35 AM PST Researchers have trained computers to predict the next designer drugs before they are even on the market, technology that could save lives. Identifying these so-called 'legal highs' within seized pills or powders can take months, during which time thousands of people may have already used a new designer drug. But new research is already helping law enforcement agencies around the world to cut identification time down from months to days, crucial in the race to identify and regulate new versions of dangerous psychoactive drugs. |
COVID patients on SSRI antidepressants are less likely to die, study finds Posted: 15 Nov 2021 09:35 AM PST A large analysis of health records from 87 health care centers across the United States found that people taking a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine, were significantly less likely to die of COVID-19 than a matched control group. |
Posted: 15 Nov 2021 09:35 AM PST New research has shown the drug losartan, normally used to treat high blood pressure (hypertension), is not effective in slowing down the progression of Alzheimer's disease (AD) in people with mild-to-moderate disease after 12 months of treatment. However, the drug could still be of benefit if prescribed for longer and if given to people with very early disease. |
Researchers target a mouse’s own cells, rather than using antibiotics, to treat pneumonia Posted: 15 Nov 2021 09:35 AM PST Researchers have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. The method involves white blood cells of the immune system called macrophages that eat bacteria, and a group of compounds that are naturally produced in mice and humans called epoxyeicosatrienoic acids or EETs. |
A key brain region responds to faces similarly in infants and adults Posted: 15 Nov 2021 09:35 AM PST In a functional magnetic resonance imaging study of babies ranging in age from two to nine months, researchers have found regions of the infant visual cortex that show strong preferences for either faces, bodies, or scenes, just as they do in adults. |
Keeping chocolate milk smooth, stable without carrageenan Posted: 15 Nov 2021 09:35 AM PST Fat-free chocolate milk processed for the first time with high-pressure jet technology exhibits enhanced viscosity, stabilizing cocoa particles in the fluid and eliminating the need for adding a controversial emulsifier. That's the conclusion of a team of researchers, whose study suggests that the new technology can preclude the use of carrageenan in chocolate milk. The widely used food additive -- which helps keep the liquid smooth and well-mixed even after days sitting on a store shelf -- is not desired by many consumers, especially in organic chocolate milk. |
Lab mimics molecule found in poppies Posted: 15 Nov 2021 09:35 AM PST An undergraduate leads the discovery of a way to synthesize a rare molecule drawn from poppies. The molecule could become a building block for painkillers and other drugs. |
Posted: 15 Nov 2021 09:35 AM PST A simple surgical technique during cardiac surgery was associated with a 56 percent reduction in the incidence of an irregular heart rhythm known as atrial fibrillation that can lead to stroke, with no added risks or side effects, according to a new study. The findings suggest that the method, called posterior left pericardiotomy, has significant potential for preventing prolonged hospital stays and the need for additional interventions and drugs to reduce the risk of strokes and heart failure associated with atrial fibrillation. |
Altered fat metabolism, enzyme, likely plays key role in Lou Gehrig’s disease Posted: 15 Nov 2021 09:35 AM PST A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig's disease. |
Using T cells to target malignant brain tumors Posted: 15 Nov 2021 09:34 AM PST Doctors and scientists have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice. |
Dreaming of being an investment shark? Better figure out if you’re an ‘owl’ or a ‘lark,’ study finds Posted: 15 Nov 2021 09:34 AM PST If you're a night owl looking to invest in the next big startup, making that decision first thing in the morning might not be the best idea, according to a new study. |
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