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‘Gut bugs’ can drive prostate cancer growth and treatment resistance Posted: 07 Oct 2021 11:59 AM PDT Common gut bacteria can become 'hormone factories' - fuelling prostate cancer and making it resistant to treatment, a new study shows. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy -- by providing an alternative source of growth-promoting androgens, or male hormones. The findings, once further validated in the clinic, could provide new opportunities for the treatment of prostate cancer through manipulation of the microbiome. |
Ten millennia of hepatitis B virus evolution described Posted: 07 Oct 2021 11:58 AM PDT Researchers uncover the evolution of the hepatitis B virus since the Early Holocene by analyzing the largest dataset of ancient viral genomes produced to date. |
Scientists assemble a biological clock in a test tube to study how it works Posted: 07 Oct 2021 11:58 AM PDT Daily cycles in virtually every aspect of our physiology are driven by biological clocks (also called circadian clocks) in our cells. The cyclical interactions of clock proteins keep the biological rhythms of life in tune with the daily cycle of night and day, and this happens not only in humans and other complex animals but even in simple, single-celled organisms such as cyanobacteria. A team of scientists has now reconstituted the circadian clock of cyanobacteria in a test tube, enabling them to study rhythmic interactions of the clock proteins in real time and understand how these interactions enable the clock to exert control over gene expression. |
Promising results for Parkinson's disease treatment Posted: 07 Oct 2021 11:58 AM PDT Researchers have found a way to make deep brain stimulation (DBS) more precise, resulting in therapeutic effects that outlast what is currently available. The work will significantly advance the study of Parkinson's disease. |
A 'cousin' of Viagra reduces obesity by stimulating cells to burn fat Posted: 07 Oct 2021 09:22 AM PDT Researchers have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function -- without changes in food intake or daily activity. |
Small molecules with a dual function Posted: 07 Oct 2021 09:22 AM PDT Researchers have deciphered a molecular mechanism with which a small RNA and a small protein regulate the metabolism of cholera bacteria and the production of the cholera toxin. |
Higher levels of education and higher income mean better health for older adults Posted: 07 Oct 2021 09:22 AM PDT A new cross-national study comparing multimorbidity disease cluster patterns, prevalence and health risk factors across Ireland, England, The United States and Canada, reveal important findings that could have health implications for public health policy.The study investigates lifetime prevalence of 10 common chronic, cardiovascular and mental health conditions among 62,111 older adults aged 52-85 years of age across the four countries, and uncovers how differences in demographics, socio-economic status and health behaviours affect the combination of diseases within and across four countries. |
Colorblind fish show experts how vision evolved Posted: 07 Oct 2021 09:21 AM PDT After decades of studying color vision in mice, new research in zebrafish has allowed experts to uncover how some animals regulate their ability to see blue light. The results allow researchers to better understand the evolutionary history and current control mechanisms of color vision. |
Screen time linked to risk of myopia in young people Posted: 07 Oct 2021 09:21 AM PDT A new study has revealed a link between screen time and higher risk and severity of myopia, or short-sightedness, in children and young adults. |
Flying high-speed drones into the unknown with AI Posted: 07 Oct 2021 09:21 AM PDT Researchers have developed a new approach to autonomously fly quadrotors through unknown, complex environments at high speeds using only on-board sensing and computation. The new approach could be useful in emergencies, on construction sites or for security applications. |
Beyond childhood: Picky eating in college students Posted: 07 Oct 2021 07:10 AM PDT Looking beyond the picky eating of childhood, researchers looked at this behavior in college students. Self-identified picky eaters ate significantly less fiber and vegetables and reported greater levels of social phobia than non-picky eaters, according to a new study. Social phobia is the fear of being evaluated during everyday activities by others. |
Gel enhances CAR-T immunotherapy benefits in brains surgically treated for glioblastoma Posted: 06 Oct 2021 11:34 AM PDT Researchers report that pairing a newly developed fibrin gel with CAR-T immunotherapy that was delivered to post-surgical mouse brains with glioblastoma improved the immunotherapy's effectiveness. The gel aided CAR-T cell distribution in the brain by acclimating the T cells to the post-surgical wound environment while also stopping the tumor from recurring. |
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