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ScienceDaily: Top Health News |
| CRISPR gene editing tech lead to new insights about hypertrophic cardiomyopathy Posted: 12 Aug 2021 01:18 PM PDT Hypertrophic cardiomyopathy (HCM) is the most common of all genetic heart diseases and is the leading cause of sudden cardiac death. It is characterized by an abnormal thickening of the heart muscle, which over time can lead to cardiac dysfunction and, ultimately, heart failure. |
| A mobility-based approach to optimize pandemic lockdown strategies Posted: 12 Aug 2021 11:50 AM PDT A new strategy for modeling the spread of COVID-19 incorporates smartphone-captured data on people's movements and shows promise for aiding development of optimal lockdown policies. |
| Posted: 12 Aug 2021 11:50 AM PDT Abnormal cells that go on develop into esophageal cancer -- cancer that affects the tube connecting the mouth and stomach -- start life as cells of the stomach, according to scientists. The study found that a particular subtype of esophageal cancer known as esophageal adenocarcinoma is always preceded by Barrett's esophagus -- abnormal cells of the esophagus -- even if these cells are no longer visible at the time of cancer diagnosis. This confirms that screening for Barrett's is an important approach to esophageal cancer control. |
| Metabolism changes with age, just not when you might think Posted: 12 Aug 2021 11:50 AM PDT Most of us remember a time when we could eat anything we wanted and not gain weight. But a new study suggests your metabolism, the rate at which you burn calories, actually peaks much earlier and starts its inevitable decline later than you might think. |
| Red blood cell alterations contribute to lupus Posted: 12 Aug 2021 10:59 AM PDT The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a new study. The discovery could lead to new methods for classifying and treating patients with this disease. |
| Toward next-generation brain-computer interface systems Posted: 12 Aug 2021 10:59 AM PDT A new kind of neural interface system that coordinates the activity of hundreds of tiny brain sensors could one day deepen understanding of the brain and lead to new medical therapies. |
| Scrap the nap: Study shows short naps don’t relieve sleep deprivation Posted: 12 Aug 2021 09:31 AM PDT The latest study shows that short naps are ineffective in mitigating the potentially dangerous cognitive effects of sleep deprivation. |
| From blood to brain: Delivering nucleic acid therapy to the CNS Posted: 12 Aug 2021 09:31 AM PDT Researchers have developed a drug delivery platform wherein heteroduplex oligonucleotide drugs conjugated with cholesterol are able to cross the blood-brain barrier and achieve therapeutic concentrations in the central nervous system even with intravenous or subcutaneous dosing. The ability to target gene expression in the central nervous system through systemically administered nucleic acid therapy holds great promise for the treatment of neurogenerative disease. |
| Ultrasound remotely triggers immune cells to attack tumors in mice without toxic side effects Posted: 12 Aug 2021 09:31 AM PDT A new cancer immunotherapy pairs ultrasound with specially engineered CAR T cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice. |
| Philippine Ayta people have the most Denisovan DNA, study finds Posted: 12 Aug 2021 09:30 AM PDT Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers have discovered that the Ayta Magbukon in the Philippines have the highest level of Denisovan ancestry in the world. In fact, they carry considerably more Denisovan DNA than the Papuan Highlanders, who were previously known as the present-day population with the highest level of Denisovan ancestry. |
| In HIV prevention, worsening disparities among U.S. states Posted: 12 Aug 2021 07:34 AM PDT States with low initial use of HIV-prevention drugs are continuing to fall behind in usage among people at risk for the disease, a new study finds. |
| Batters move their heads to keep their eyes on the ball Posted: 12 Aug 2021 06:27 AM PDT Researchers are revisiting an age-old question in baseball: Do batters actually keep their eye on the ball? A review of the few film- and lab-based studies on the subject suggests that yes, indeed, batters' eyes are watching the pitched ball. But they're moving their heads, and not their eyes, to direct their gaze. |
| For psoriasis, targeting skin protein may help control inflammation Posted: 12 Aug 2021 06:27 AM PDT Results from a new study reveal that targeting interferon kappa, a protein made by skin cells, may reduce the severity of psoriasis. Researchers say the findings will bring physicians one step closer to optimizing treatments for patients with the autoimmune disease. |
| Posted: 12 Aug 2021 06:27 AM PDT Scientists used a new system to zoom in on an iconic RNA catalyst and a piece of viral RNA that's a potential target for COVID-19 treatments. |
| Discovery raises possibility of new medication for Alzheimer’s, Parkinson’s Posted: 12 Aug 2021 06:27 AM PDT Researchers have for the first time demonstrated it's possible to use a synthetic thyroid hormone to regulate a gene implicated in neurodegenerative diseases like Alzheimer's, Parkinson's and multiple sclerosis. |
| New technique illuminates DNA helix Posted: 12 Aug 2021 06:27 AM PDT Researchers have identified a new way to measure DNA torsional stiffness -- how much resistance the helix offers when twisted -- information that can potentially shed light on how cells work. |
| Silica nanostructure with chemo-enzymatic compartmentalization Posted: 12 Aug 2021 06:27 AM PDT A research team has recently synthesized a chemo-enzymatic nanostructure that can selectively synthesize one enantiomer while acting like an artificial organelle in the cell. |
| Posted: 12 Aug 2021 06:27 AM PDT A new study suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research. |
| Increasing the immune system’s appetite for cancer protectors Posted: 11 Aug 2021 01:28 PM PDT A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could lead to new types of cancer immunotherapies. |
| Potential new treatment for deadly blood cancer Posted: 11 Aug 2021 10:15 AM PDT A drug used to treat certain advanced breast cancers may offer a new treatment option for a deadly blood cancer known as myelofibrosis, new research suggests. |
| Posted: 11 Aug 2021 10:15 AM PDT A cell culture study maps mechanisms underlying a new potential strategy for killing pancreatic cancer cells through a type of cell death known as ferroptosis. |
| Lyme disease heightens risk of mental disorders, suicidality Posted: 11 Aug 2021 08:31 AM PDT A new study reports that patients hospitalized with Lyme disease had a 28 percent higher rate of mental disorders and were twice as likely to attempt suicide. Physicians and patients should be aware of the potential for psychiatric symptoms post-Lyme infection, particularly during the first year after diagnosis. |
| Study of skull birth defect takes it from the top Posted: 11 Aug 2021 08:31 AM PDT A new study presents a detailed cellular atlas of the developing coronal suture, the one most commonly fused as a consequence of single gene mutations, leading to birth defects such as craniosynostosis. With an aim toward advancing new interventions for patients, researchers created the first detailed cell-by-cell description of how this suture develops. They identified 14 distinct types of cells in and around the developing suture and new genes that may be involved in generating and maintaining the stem cells that grow the skull bones on either side of the suture. |
| Deep learning model classifies brain tumors with single MRI scan Posted: 11 Aug 2021 07:08 AM PDT A team of researchers have developed a deep learning model that is capable of classifying a brain tumor as one of six common types using a single 3D MRI scan, according to a new study. |
| Posted: 11 Aug 2021 06:16 AM PDT Those youngest in a class were more likely to experience low educational achievement, substance misuse disorder, and depression in later life. However, younger children with ADHD appeared less at risk of depression. |
| New technique identifies proteins in the living brain Posted: 11 Aug 2021 06:15 AM PDT In the new study, researchers designed a virus to send an enzyme to a precise location in the brain of a living mouse. Derived from soybeans, the enzyme genetically tags its neighboring proteins in a predetermined location. After validating the technique by imaging the brain with fluorescence and electron microscopy, the researchers found their technique took a snapshot of the entire set of proteins (or proteome) inside living neurons, which can then be analyzed postmortem with mass spectroscopy. |
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