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Cellular therapy improves signs and symptoms of Duchenne muscular dystrophy Posted: 10 Mar 2022 03:59 PM PST A recent clinical trial has shown that cellular therapy is safe and effective in stopping the deterioration of upper limb and heart functions in patients with late-stage Duchenne muscular dystrophy. |
Home-based flu tests as accurate as rapid diagnostic testing in clinical settings Posted: 10 Mar 2022 02:08 PM PST Home-based, self-administered tests for influenza are comparable in accuracy to rapid diagnostic tests in clinical settings, according to a peer-reviewed study. The researchers determined that sensitivity and specificity of the home test and clinical test were similar. False-negative results were more common when the self-test was administered after 72 hours of the onset of symptoms, but were not related to inadequate swab collection or severity of illness. |
Brain-based computing chips not just for AI anymore Posted: 10 Mar 2022 02:08 PM PST With the insertion of a little math, researchers have shown that neuromorphic computers, which synthetically replicate the brain's logic, can solve more complex problems than those posed by artificial intelligence and may even earn a place in high-performance computing. Neuromorphic simulations employing random walks can track X-rays passing through bone and soft tissue, disease passing through a population, information flowing through social networks and the movements of financial markets. |
Human induced pluripotent stem cells improve visual acuity, vascular health Posted: 10 Mar 2022 02:08 PM PST Researchers are investigating novel regenerative medicine approaches to better manage vascular health complications from type 2 diabetes that could someday support blood vessel repair in the eye among diabetic patients with early retinal vascular dysfunction. |
Watershed size plays major role in filtering pollutants, researchers find Posted: 10 Mar 2022 02:08 PM PST Research has found that watershed size plays a major role in a river network's ability to do this work. The findings further the understanding of which estuaries and coastal areas will be more impacted by human development in their watersheds and also casts a light on the intricacies of the global carbon cycle. |
Antivirals, some antibodies, work well against BA.2 omicron variant of COVID-19 virus Posted: 10 Mar 2022 02:08 PM PST The antiviral therapies remdesivir, molnupiravir, and the active ingredient in Pfizer's Paxlovid pill (nirmatrelvir), remain effective in laboratory tests against the BA.2 variant of SARS-CoV-2, the virus that causes COVID-19, according to new research. |
Scientists 'supercharge' cancer-fighting T cells Posted: 10 Mar 2022 02:08 PM PST Scientists have identified a way to 'supercharge' tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat. |
New study confirms bioengineered RSV protein vaccine evokes protective immune response Posted: 10 Mar 2022 02:08 PM PST Researchers marked a major milestone in the effort to create an effective vaccine for respiratory syncytial virus (RSV), which can cause severe respiratory disease in children and the elderly. |
Gamification, past habits may impact future eco-friendly tendencies differently Posted: 10 Mar 2022 02:08 PM PST Green consumer habits may not be impacted by gamification practices, but people who purchased environmentally friendly products in the past are likely to continue to do so, according to a team of researchers, who theorized that adding gamification techniques to a consumer's eco-friendly purchasing habits would perpetuate green consumerism. |
Labeling key to success of software company innovations Posted: 10 Mar 2022 12:19 PM PST Companies in the software industry, where novel ideas are prized, use linguistic tactics to develop new labels for their innovations to stay ahead of competitors. |
Cosmic particle accelerator at its limit Posted: 10 Mar 2022 11:37 AM PST With the help of special telescopes, researchers have observed a cosmic particle accelerator as never before. Observations made with the gamma ray observatory H.E.S.S. in Namibia show for the first time the course of an acceleration process in a stellar process called a nova, which comprises powerful eruptions on the surface of a white dwarf. A nova creates a shock wave that tears through the surrounding medium, pulling particles with it and accelerating them to extreme energies. Surprisingly, the nova 'RS Ophiuchi' seems to cause particles to accelerate at speeds reaching the theoretical limit, corresponding to ideal conditions. |
Recently discovered protein turbocharges gene expression Posted: 10 Mar 2022 11:37 AM PST Scientists have found intriguing new details about a previously missing critical factor in gene expression. An ancient protein called NDF found in all human tissues enhances gene activation and may be involved in diseases such as cancer. |
Heat stress for cattle may cost billions by century's end, study finds Posted: 10 Mar 2022 11:37 AM PST Climate change poses a potentially devastating economic threat to low-income cattle farmers in poor countries due to increasing heat stress on the animals. Globally, by the end of this century those producers may face financial loss between $15 and $40 billion annually. |
Prenatal mindfulness program improves stress response in infants Posted: 10 Mar 2022 11:37 AM PST Infants whose mothers participated in a mindfulness-based program during pregnancy had healthier stress responses at 6 months old, a new study found. |
Cancer patients do benefit from COVID-19 vaccination, study finds Posted: 10 Mar 2022 11:37 AM PST A recent study followed 515 patients with varying cancers. The goal was to evaluate if patients had an immune response to the Moderna mRNA-1273 vaccine and if that response differed by diagnosis and treatment. |
ECMO may offer sickest COVID patients chance for 'exceptional survival', study finds Posted: 10 Mar 2022 11:37 AM PST Some patients with severe COVID-19 who are treated with extracorporeal membrane oxygenation (ECMO) may experience significant lung recovery and return to normal lives with 'meaningful' long-term outcomes, according to research. |
New observations from ICESat-2 show remarkable Arctic sea ice thinning in just three years Posted: 10 Mar 2022 11:37 AM PST Over the past two decades, the Arctic has lost about one-third of its winter sea ice volume, largely due to a decline in sea ice that persists over several years, called multiyear ice, according to a new study. The study also found sea ice is likely thinner than previous estimates. Seasonal sea ice, which melts completely each summer rather than accumulating over years, is replacing thicker, multiyear ice and driving sea ice thinning trends, according to the new research. |
Damage to inner ear system predicts fall risk among people with Alzheimer's disease Posted: 10 Mar 2022 11:37 AM PST A study of about 50 people with Alzheimer's disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients' well-documented higher risk of falling. |
Ice-ocean interactions are accelerating melting in West Antarctica Posted: 10 Mar 2022 11:37 AM PST An analysis of Antarctica's Pope, Smith and Kohler glaciers has revealed an aggressive pattern of retreat connected to high melt rates of floating ice in the Amundsen Sea Embayment sector of West Antarctica. |
Magnetism helps electrons vanish in high-temp superconductors Posted: 10 Mar 2022 11:37 AM PST A physicist's discovery could lead to the engineering of high-temp superconducting properties into materials useful for quantum computing, medical imaging. |
Researchers discover genetic cause of sometimes deadly esophageal disorder in dogs Posted: 10 Mar 2022 11:37 AM PST German shepherds are predisposed to congenital idiopathic megaesophagus (CIM), an inherited disorder where a puppy develops an enlarged esophagus that fails to move food into their stomachs. Puppies with the condition regurgitate their food and fail to thrive, often leading to euthanasia. Researchers have now developed a genetic test for the disease that German shepherd dog breeders can use to reduce the risk that puppies in future litters will develop the disease. |
Water determines magma depth, a key to accurate models of volcanic activity, eruption Posted: 10 Mar 2022 11:37 AM PST Around the world, between 40 and 50 volcanoes are currently erupting or in states of unrest, and hundreds of millions of people are at risk of hazards posed by these potentially active volcanos. Yet, despite the profound hazards posed to human life and property by volcanic eruptions, humanity still cannot reliably and accurately predict them, and even when forecasts are accurately made by experts, they may not afford ample time for people to evacuate and make emergency preparations. |
After more than 20 years, scientists have solved the full-length structure of a Janus Kinase Posted: 10 Mar 2022 11:36 AM PST More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers. |
Addressing knowledge gaps in shark and ray research Posted: 10 Mar 2022 08:51 AM PST Sharks and rays are one of the most ancient vertebrate groups, as well as one of the most endangered. Researchers still know very little about many shark and ray species and the environments in which they live, particularly rare species and those that dwell in remote areas, where resources and capacity for conducting study and monitoring are scarce. |
How toddler-mother attachment impacts adolescent brain and behavior Posted: 10 Mar 2022 08:51 AM PST Interpersonal trust is a crucial component of healthy relationships. When we interact with strangers, we quickly gauge whether we can trust them. And those important social skills may be shaped by our earliest relationship with caregivers. Adolescents who had an insecure attachment to their mothers as toddlers are more likely to overestimate the trustworthiness of strangers, according to a new study from the University of Illinois. |
Hawaiian corals show surprising resilience to warming oceans Posted: 10 Mar 2022 08:51 AM PST A long-term study of Hawaiian coral species provides a surprisingly optimistic view of how they might survive warmer and more acidic oceans resulting from climate change. |
Genetic mechanisms of coral metamorphosis identified Posted: 10 Mar 2022 08:51 AM PST Researchers discovered the gene expression regulation mechanisms that drive coral transition from a floating larvae to one that sits sedentary in reefs. |
Predicting tropical fish patterns in Japan Posted: 10 Mar 2022 08:51 AM PST Scientists have developed a model that predicts six tropical fish species will expand into northern parts of Japan as sea temperatures rise. |
Using cell phone GNSS Networks to monitor crustal deformation Posted: 10 Mar 2022 08:51 AM PST The Global Navigation Satellite System associated with a Japanese cell phone carrier can enhance monitoring of crustal deformation changes for earthquake early warning models. |
The cellular cleaning program autophagy helps in wound healing Posted: 10 Mar 2022 08:51 AM PST Scientists have shown that the recycling program of cells, autophagy, leads to the fusion of several single cells into multinucleated cell units during wound healing. |
A cautionary tale of machine learning uncertainty Posted: 10 Mar 2022 08:51 AM PST A new analysis shows that researchers using machine learning methods could risk underestimating uncertainties in their final results. |
On the hunt for ultra-thin materials using data mining Posted: 10 Mar 2022 08:51 AM PST Two-dimensional (2D) materials possess extraordinary properties. They usually consist of atomic layers that are only a few nanometers thick and are particularly good at conducting heat and electricity, for instance. To the astonishment of many scientists, it recently became known that 2D materials can also exist on the basis of certain metal oxides. These oxides are of great interest in areas such as nanoelectronics applications. A research team has now succeeded in predicting twenty-eight representatives of this new class of materials by using data-driven methods. |
The start of the birth of planets in a binary star system observed Posted: 10 Mar 2022 08:51 AM PST Astronomers have observed primordial material that may be giving birth to three planetary systems around a binary star in unprecedented detail. |
Posted: 10 Mar 2022 08:51 AM PST Animals often use highly specific signals to warn their herd about approaching predators. Surprisingly, similar behaviors are also observed among plants. Shedding more light on this phenomenon, researchers have discovered one such mechanism. Using Arabidopsis thaliana as a model system, the researchers have shown that herbivore-damaged plants give off volatile chemical 'scents' that trigger epigenetic modifications in the defense genes of neighboring plants. These genes subsequently trigger anti-herbivore defense systems. |
A first step towards quantum algorithms: Minimizing the guesswork of a quantum ensemble Posted: 10 Mar 2022 08:51 AM PST A quantum ensemble -- a set of quantum states with their corresponding probabilities -- is essential to the encoding of classical information for transmission over quantum channels. But receivers must be able to 'guess' the transmitted quantum state, incurring a cost called 'guesswork.' Recently, researchers have derived analytical solutions of the guesswork problem for when the ensemble is subject to a finite set of conditions. The results constitute a first step towards future algorithms for quantum software. |
One step closer to artificial rhino eggs Posted: 10 Mar 2022 08:51 AM PST To prevent the extinction of the northern white rhino, researchers are attempting to create artificial egg cells from stem cells. A team has now revealed that they are one step closer to achieving this goal. |
Blood test as possible diagnostic tool for Alzheimer’s disease Posted: 10 Mar 2022 08:50 AM PST A recent study shows promising results for a blood test that could be used to identify Alzheimer's changes in the brain before the onset of any symptoms, which could result in preventative treatments being used before any memory loss. |
Could leaky blood vessels in the brain be a culprit in Alzheimer’s disease? Posted: 10 Mar 2022 08:50 AM PST Researchers report that they found high levels of the protein Fli-1 in the brains of deceased Alzheimer's patients. Blocking Fli-1's action in a mouse model of Alzheimer's disease reversed mental loss and reduced the brain inflammation and amyloid-beta clumping that are hallmarks of Alzheimer's disease. Although clinical translation of this finding is likely years off, the study suggests Fli-1 is a promising therapeutic target for Alzheimer's disease. |
Exploring ancient tuberculosis transmission chains Posted: 10 Mar 2022 08:50 AM PST Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers found that ancient TB discovered in archaeological human remains from South America is most closely related to a variant of TB associated today with seals, but surprisingly these cases were found in people who lived nowhere near the coast. This implies that these cases were not the result of direct transmission from seals, and instead one, or more, spillover events were likely to be the primary drivers of human infection. |
The new, improved Dragonfly is a galactic gas detector Posted: 10 Mar 2022 08:50 AM PST The Dragonfly telescope is undergoing a metamorphosis. For the past decade, the Dragonfly Telephoto Array has conducted groundbreaking science by detecting faint starlight within dimly lit parts of the night sky. The telescope uses clusters of telephoto lenses to create images, much the way a dragonfly's eyes gather visual data. |
Rear-end collision on the 'ribosome highway' Posted: 10 Mar 2022 08:50 AM PST As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins. For a number of reasons, this process can fail, leaving the ribosome stalled on the mRNA and bringing synthesis of the protein to a halt. An international research team has now identified a bacterial protein called MutS2 that senses and rescues these stuck protein factories. |
More 'losers' than 'winners' among plants in the age of humans Posted: 10 Mar 2022 08:50 AM PST A new analysis spanning more than 86,000 plant species finds that on this human-dominated planet, many more species of plants are poised to 'lose' rather than 'win.' T |
Seeing lipids more deeply with mass spectrometry Posted: 10 Mar 2022 08:43 AM PST PRMC-MS allows enhanced profiling of phosphoinositide acyl variants both in intracellular and extracellular environments. |
Cutting HFCs to cool the Earth Posted: 10 Mar 2022 08:42 AM PST To have a better chance of holding global warming to 1.5°C, we need to accelerate the phase-down of HFC refrigerants under the Montreal Protocol. This could also reduce pollution and improve energy access. |
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