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Findings open the way to more precise diagnoses and treatments of Alzheimer’s disease Posted: 05 Jan 2022 12:13 PM PST An international team has made a significant breakthrough in understanding why Alzheimer's disease progresses so rapidly in some people that they die within three years. The researchers found a link between strains of misshapen and fast-replicating tau protein and accelerated cognitive decline -- a critical result that illuminates the variations in Alzheimer's disease and could help lead to more precise diagnoses and targeted therapies. Such work could lead to changes in Alzheimer's care, possibly giving patients and families more accurate prognoses. |
Timing of brain injury in pregnancy, birth may impact motor and language outcomes Posted: 05 Jan 2022 12:13 PM PST A new study that mapped the neural connections of newborns with two different kinds of brain injuries found the maps looked very different -- and were linked to significantly different developmental outcomes years later. |
How a brain networks enables human conversation Posted: 05 Jan 2022 10:45 AM PST A new study has identified a brain circuit that is active while we plan our spoken replies during conversation. The work promises to guide the design of new therapies for the 7.5 million Americans who have trouble using their voices, say the study authors. |
Adult epilepsy treatment reduces seizures in children Posted: 05 Jan 2022 07:32 AM PST A surgical treatment commonly used to reduce epileptic seizures in adults also is effective and safe for children, according to a new study. The study is one of the first to investigate responsive neurostimulation system (RNS)--a device similar to a pacemaker that sends electric charges to the heart, which delivers stimulation directly to the brain when needed to prevent seizures--in children. |
Researchers urge: 'Prescribe aspirin based on benefit-to-risk not age' Posted: 05 Jan 2022 06:45 AM PST Recent guidelines have restricted aspirin use in the primary prevention of cardiovascular disease to patients under 70, and more recent guidance to patients under 60. Yet, the risks of heart attacks and strokes increase markedly with age. Researchers urge that to do the most good for the most patients in primary prevention of heart attacks and strokes, health care providers should make individual clinical judgements about prescribing aspirin on a case-by-case basis and based on benefit-to-risk not age. They conducted an updated meta-analysis, which adds the results of the four recent trials to the previous comprehensive meta-analysis of six earlier major trials, and aspirin produced a statistically significant 13 percent reduction in cardiovascular disease with similar benefits at older ages in each of the individual trials. |
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