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| | | Researchers examined the association between COVID-19 infection and risk for diabetes in a population-based cohort study. Individuals who tested positive for SARS-CoV-2 infection were matched on sex, age, and collection date of test to those who tested negative in a 1:4 ratio (125,987 and 503,948 individuals, respectively). |
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The history of metformin can be traced back to the Middle Ages when traditional healers used extracts of a plant called Galega officinalis, also known as French lilac or goat’s rue, to treat diabetes. In the 1920s, researchers discovered that a compound called guanidine, which is present in Galega, had antidiabetic effects. However, guanidine was found to have serious side effects and was not suitable for use as a medicine. |
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Colleagues examined the effect of bariatric surgery on diabetes complications among individuals with class II/III obesity. Participants underwent metabolic phenotyping and diabetes complication assessments at baseline and two years following surgery. Seventy-nine of the 127 baseline participants completed in-person follow-up. |
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