HSE has received testing proposals to undertake testing in vertebrates to consider and evaluate. Article 40(2) of the UK REACH Regulation requiresâ¯HSEâ¯to invite third parties to submit scientifically valid information and studies that are relevant to the hazard endpoints for which vertebrate testing is proposed. These submissions will be considered and evaluated alongside the proposals submitted by the registrants.    Any interested third parties are invitedâ¯to provide such information and studies that address the substances and hazard endpoints below. Information can be submitted by any member of the public or interested party.   Consultation details for the endpoints for which testing is proposed can be viewed by following the links below:  Reaction product of propylidynetrimethanol, propoxylated, reaction products with ammonia and 2,2-Dimethyl-3-(4-morpholinyl)propanal
CAS: 1379822-00-0 and EC: 700-879-7 Â Repeated dose toxicity (sub-chronic 90 day) Â Reproductive toxicity (pre-natal developmental toxicity) Â N-[3-({[2,2-dimethyl-3-(morpholin-4-yl)propylidene]amino}methyl)-3,5,5-trimethylcyclohexyl]-2,2-dimethyl-3-(morpholin-4-yl)propan-1-imine
CAS: 1217271-02-7 and EC: 700-584-3 Â Repeated dose toxicity (sub-chronic 90 day) Â Reproductive toxicity (pre-natal developmental toxicity) Â Scientific and technical information relevant to the hazard endpoints should be submitted directly to HSE using the commenting webform and templates by 2Â May 2024. | 