It's time to start setting your Week 16 lineups, and we're beginning our week-long advice with analysis of running back matchups and projections. Devin Singletary and Carlos Hyde are coming off rock-solid performances, but can you trust them facing strong defenses? Conversely, Marlon Mack and Devonta Freeman struggled in Week 15, yet there is reason to believe they could be championship-winners this week. We're previewing the best and worst of the running back position for Week 16 in our Start 'Em & Sit 'Em and RB Preview columns.

Plus, we have injury updates from Ben Gretch, getting you up to date on the statuses of Chris Godwin, Dalvin Cook, Julian Edelman and others.

Get help with setting your lineup in Week 16 with Jamey Eisenberg's look at his top starts and sits at running back, including his two Starts of the Week.

Ben Gretch gets you up to speed on the latest headlines for Fantasy Football in Week 16, including the status of two superstars.

Here's what you need to know about running back for Week 16, including projections from Heath Cummings.