A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.
Researchers report a novel aminopolycarboxylic acid lipid-embedded porphyrin nanoparticle and elucidated its unique cellular delivery mechanism that affords its enhanced intracellular uptake, fast fluorescence activation, and superior photodynamic therapeutic (PDT) efficacy.
