Cancer Research ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
| | | | Our new image campaign – Research is beautiful – is now open for entries. We’re looking for captivating images that showcase your research. It could be your science from the microcosm to the macrocosm; you and your fellow researchers in action; as well as research environments spanning from the lab to research events. Anything that captures your work, or your passion for your work is welcome.
Email us your photos now. T&Cs apply.
Stay tuned to #ResearchIsBeautiful on our social media for our monthly picks. |
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Funding & Research Opportunities |
| Get in touch with our office for confidential advice on eligibility, remit and funding options prior to applying. |
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| | | | | | | | | | | | Applications accepted all year round |
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| | | | | | Applications accepted all year round |
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| | | | | | Applications accepted all year round |
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| | | | | | Applications accepted all year round |
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| | Catch us at #PrevConf24 debate session: chemoprevention is dead? |
| Our head of prevention research, David Crosby, will be chairing a debate session at our Cancer Prevention Research Conference on 25-27 June in Boston on the future of chemoprevention.
Join Karen Brown (University of Leicester) and Scott Lippman (University of California, San Diego) as they exchange views upon the past decades of prevention research with drugs or compounds taken from dietary and natural sources in the context of future precision intervention modalities.
Follow #PrevConf24 on our social channels for more conference updates. |
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| | | | At this year’s AACR in San Diego, Jean Abraham and Karen Pinilla from our Cambridge Centre Precision Breast Cancer Institute presented results of PARTNER, a Phase 2-3 trial for patients with triple negative breast cancer (TNBC) or breast cancer caused by an inherited BRCA mutation.
Results from the TNBC cohort, published in Nature, showed that adding targeted drug olaparib to platinum-based chemotherapy before surgery did not improve outcomes for patients with TNBC. The study has led to a more optimal chemotherapy regime for these patients, and continued research on the extensive sample and data resource will help us to understand TNBC better in order to identify better treatments. | | |
| | | | | | Register now for our Postdoc Futures event on 7 June in Manchester.
This is your chance to discover the career opportunities within and outside academia, learn about our training and funding programmes available, and pick up practical tips and tools to help you progress your career.
Stop by our mini-careers fair during the breaks to chat with representatives from different sectors. There will be booths from our Fellowships team, our Manchester Institute, Cancer Research Horizons, and Science Solutions, a scientific recruitment company.
There is no charge to attend this event, with a full ticket refund following your attendance at the event (excluding the eventbrite fee). | | |
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| | #CRUKFunded: New insights into the interplay between diet the microbiome and the immune system |
| In a paper recently published in Science, researchers found that vitamin D rich diets could improve cancer immunity.
The study, headed up by Evangelos Giampazolias, Group Leader of the Cancer Immunosurveillance Group at Cancer Research UK Manchester Institute and Caetano Reis e Sousa, senior Group Leader at the Francis Crick Institute, gave mice diets rich in vitamin D. They found the vitamin D acted on epithelial cells in the intestine, promoting growth and improving the metabolic qualities of the bacteria Bacteroides fragilis, which in turn boosts T-cell responses to cancer. How B.fragilis acts to improve tumour immunity remains unknown, but the study findings point towards MyD88-dependent receptor signalling and type I IFN production as potential key factors.
The researchers further investigated this effect in humans by analysing a dataset of 1.5m people in partnership with the Aalborg University in Denmark, which highlighted a link between lower vitamin D levels and a higher risk of cancer. A separate analysis also found a positive link between cancer patients with higher levels of vitamin D and response to immunotherapy. |
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On our way to a smokefree UK |
| MPs in Westminster voted last month to take us one step closer to enacting historic legislation to raise the age of sale of tobacco.
This is a huge step forward for our Smokefree UK campaign. Thank you to everyone who helped us get here by contributing to the public consultation back in November. We’re now looking to see this legislation move swiftly through the UK Parliament and be implemented across all four UK nations. |
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| | | | The Molecular Analysis for Precision Oncology Congress is returning to London on 16-18 October. Get ready for three days of discussion and debate on the latest discoveries in precision medicine and translational research.
Join scientific co-chairs Mariam Jamal-Hanjani (UCL Cancer Institute), Joaquin Mateo (Vall d’Hebron Institute of Oncology) and Lisa Derosa (Gustave Roussy) to learn about current and emerging approaches in precision oncology, and potential solutions in clinical research and practice.
The congress is a partnership between us, the European Society for Medical Oncology and Unicancer. | | |
| | | | | | The NC3Rs is holding a launch meeting for its new Oncology Network on 20 May in London.
You will get the chance to learn about the 3Rs oncology models, discuss how these could be applied to new research questions, network and explore follow-on funding opportunities.
If you’re not able to attend the event, you can still become a member of the Oncology Network for email updates, Network meetings and the opportunity to provide feedback on how the NC3Rs can help best support the oncology research community. | | |
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