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| | If your research has the potential to open new therapeutic avenues for young patients, the Childhood Cancer Therapeutic Catalyst award is here to help you take your research to the next step. This funding opportunity supports researchers in the early stages of project translation, including target/pathway validation, therapeutic discovery, and innovative screenings. Managed by Cancer Research Horizons, the award funds research projects up to £250,000. This is a unique opportunity to secure funding and advance your research. Applications are open to researchers at all career stages. Expressions of interest close on 31 January 2025. |
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Funding & Research Opportunities |
| Get in touch with our office for confidential advice on eligibility, remit and funding options prior to applying. |
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| | | | | | | | | Applications accepted all year round |
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| | | | Applications accepted all year round |
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| | | | Applications accepted all year round |
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| | | | Applications accepted all year round |
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#CRUKFunded: Characterising the evolutionary dynamics of cancer proliferation
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| Simone Zaccaria (University College London Cancer Institute) and colleagues have published a paper in Nature Genetics about the development of SPRINTER, an algorithm that can measure the proliferation of distinct clones within the same tumour using DNA sequencing data obtained from thousands of single cancer cells. In an article earlier this year, Simone, one of our Career Development Fellows, took us through his single-cell DNA sequencing approach. The SPRINTER algorithm, a continuation of Simone’s work and part of the TRACERx and PEACE studies has shown that tumours and metastases can contain clones with significantly different proliferation rates, with the highest-proliferating clones importantly being the most likely to seed metastases.
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New episode of our entrepreneurial deep dive podcast series |
| In addition to the many skills of an academic, you’ll need a few more to successfully translate your research. So, what are they? What’s the best way to sharpen up? And how – exactly – can they help? It’s all in the new series of our Cancer Research Matters podcast, with Alessia Errico, Faith Howard and Matt de Vries joining the latest episode to tell us more. Patent attorney Camille Terfve also joins the pod to give us a vital primer on intellectual property protection. Whether you’re an academic researcher seeking practical advice and inspiration or just want to hear about others' translation journeys, this series has something for you. |
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Preparing your data for reuse webinar |
| Maximise the impact of your data by starting to think about your data as a potential asset and preparing for reuse from the start. Joe Day (Cancer Research Horizons) joins the next webinar in our data series to guide you through preparing your data for the highest potential of reuse and the support we provide to facilitate this, including in commercial collaborations. Through this webinar, you’ll learn about providing consent language and ethical approvals, planning for integration and standardisation and how to plan the structure of access oversight mechanisms. Tune in on 22 January 12-1 pm and ask your questions. |
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Meet this year’s final image campaign winner |
| Congratulations to Rachel Mathews, a PhD student from The University of Cambridge Cavendish Laboratory who is our December winner. Rachel’s fluorescence image shows the expression of carbonic anhydrase IX (CAIX) in the kidney cancer cell line A704. CAIX is a transmembrane protein whose over-expression is linked to the VHL mutation in clear cell renal cell carcinoma, the most common type of kidney cancer. The fluorescent labelling of the CAIX protein present in these cells allows us to see the many micro-tubule connections between the cells, revealing how each cell forms many connections to its neighbours in order to relieve the acidic environment found within a tumour and ensuring the cells’ continued survival. This bears a striking resemblance to the behaviours and needs of the research community. Just like these mammalian cells in 2D culture, connected and supported researchers are able to excel by sharing resources, knowledge and co-ordinating their efforts towards the united goal of advancing research. |
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| Together we are beating cancer |
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| You are playing a crucial role in helping us beat cancer, so we'd like to continue to keep you updated on what we're up to. You can manage your preferences and unsubscribe here. Your details are safe with us. Check out our Privacy Policy. Our supporters are at the heart of everything we achieve at Cancer Research UK. Read our Fundraising Promise. This email is from Cancer Research UK. Cancer Research UK is a registered charity in England and Wales (1089464), Scotland (SC041666), the Isle of Man (1103) and Jersey (247). A company limited by guarantee. Registered company in England and Wales (4325234) and the Isle of Man (5713F). Registered address: 2 Redman Place, London, E20 1JQ. |
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