| After hundreds of cases of mysterious illness tied to e-cigarette devices, and the death of at least six people, U.S. President Donald Trump has declared vaping a “problem.” The administration is now considering forcing companies to remove flavored versions from the market. —Josh Petri Here are today’s top stories Brexit endgame possibilities are seemingly endless. Here are four paths it may take. Mind you, chaos is also an option. WeWork is considering major changes to assuage investors ahead of the coworking startup's initial public offering. Any final decision rests with CEO Adam Neumann, who was poised to become one of the world's richest entrepreneurs before the the unicorn's prospects began to dim. Trump has discussed easing sanctions on Iran to help secure new talks. Newly-departed National Security Adviser John Bolton argued forcefully against such a move. Now three top Bolton allies have also left the administration. Apple's biggest surprise at its annual event Tuesday wasn't a new feature, device, or service—but instead an aggressive pricing strategy. Uber has generated billions of dollars from the labor of its drivers without treating them as employees. California is poised to disrupt that model. David Swensen is a legend at Yale, and its highest-paid employee. But he’s neither the president nor the football coach. He’s the money manager. What’s Joe Weisenthal thinking? The Bloomberg news director is gawking at the unfolding tragicomedy that is WeWork's attempt at an IPO. To add insult to injury, the stock market has suddenly taken a very anti-WeWork turn: tech and real estate had been among the huge winners all year, but this week they're the two worst performing sectors. What you’ll need to know tomorrow T. Boone Pickens, oilman turned raider turned trader, dies at 91. Trump will be briefed on options for new gun control measures. Purdue wins the backing of 23 states for a $12 billion opioid pact. The Hong Kong Exchange made a $36.6 billion bid for the LSE. China announces tariff exemptions, but keeps targeting U.S. farms. The Chinese Mar-a-Lago intruder was convicted of trespassing. One of the world's biggest porn sites is branching into fine art. What you’ll want to read in Businessweek About three years ago, Orig3n discovered a big problem with its DNA analysis, according to multiple former employees. Its tests were prone to errors, and a person taking the same test twice could get radically different results. Orig3n’s coders came up with a quick fix: Former workers say that if two Orig3n analyses of a particular gene didn’t match, software plugged in the earlier result. A spreadsheet shows 407 such errors that, according to a former employee, were logged over three months. Like Bloomberg’s Evening Briefing? Subscribe to Bloomberg.com. You’ll get our unmatched global news coverage and two premium daily newsletters, The Bloomberg Open and The Bloomberg Close, and much, much more. See our limited-time introductory offer. The best in-depth reporting from Asia Pacific and beyond, delivered to your inbox every Friday. Sign up here for The Reading List, a new weekly email coming this week. Download the Bloomberg app: It’s available for iOS and Android. | 