NK cell cytolytic activity is often evaluated by measuring the release of radioactive chromium-51 or indium-111 from labeled tumor cells. This application note explores a non-toxic, calcein AM release assay for evaluating NK cell cytotoxicity using image cytometry.

Researchers say they know how to track and map drug and gene delivery vehicles to evaluate which are most effective at infiltrating cells and getting to their targets, insight that could guide development of new pharmaceutical agents.

While technology has certainly changed, the R&D 100 Award's dedication to recognizing great R&D pioneers and their revolutionary ideas has remained the same.

Nanoparticles carrying two drugs can cross the blood-brain barrier and shrink glioblastoma tumors.

Graphene surface allows researchers to control cell behavior with light - a technique that could speed the search for more precise, less toxic therapeutic drugs.

Scientists have added a new dimension to the understanding of how cells alter their communication with one another during development, wound healing, and the spread of cancer.