Quantitative Systems Pharmacology (QSP) is a mathematical modeling and engineering approach to translational medicine that aims to quantitatively integrate knowledge about therapeutics with an understanding of its mechanism of action in the context of human disease mechanisms.

In this webinar, we will present a QSP Case Study which assesses a Lipid Nanoparticle to treat Crigler-Najjar Syndrome Type 1. Specifically, we will show how the QSP model was used to support translation from preclinical to clinical trials as well as first-in-human dosing.

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