Today's Rundown Idorsia's selatogrel hits goals in phase 2 cardiovascular trials Sophiris slides on prostate cancer data but vows to press on Lexicon pain drug advances after clearing early clinical test [Sponsored] Six Practices of High Performing Clinical Research Sites Entrada emerges with $59M to fund the delivery of biologic therapies into the cell Erasca picks up $42M to target biological drivers of cancer Featured Story | | | Tuesday, December 18, 2018 Idorsia's P2Y12 receptor antagonist selatogrel has significantly inhibited platelet aggregation in two phase 2 trials. The primary endpoint successes in patients with stable coronary artery disease or acute myocardial infarction set Idorsia up to plan the initiation of a phase 3 study. |
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| This week's sponsor is FierceBiotech. | | | |
Top Stories Tuesday, December 18, 2018 Sophiris Bio is adamant that it will advance its lead drug topsalysin into phase 3 testing, after a second dose showed no additional benefit in a prostate cancer trial. Tuesday, December 18, 2018 A phase 1a trial of Lexicon Pharmaceuticals’ LX9211 has met its primary objectives. The study found the AAK1 inhibitor was well tolerated, teeing Lexicon up to advance the neuropathic pain prospect. Monday, December 17, 2018 Clinical research sites have a tough, but critically important, job. It’s rigorous and precise work, but essential to the progress of medicine. Tuesday, December 18, 2018 Entrada Therapeutics has debuted with a $59 million series A and a plan to deliver biologic therapies intracellularly to treat rare and fatal monogenic diseases. Tuesday, December 18, 2018 Erasca has raised a $42 million series A round from the likes of City Hill Ventures and Cormorant Asset Management to work toward the lofty goal to “not just treat, but actually cure cancer.” Resources Sponsored by: DocuSign Life sciences companies must immediately identify and realize productivity gains to drive down operational costs—or risk seeing more nimble competitors disappear into the distance. Where to begin? Sponsored by: Veeva Learn how to spot an imposter with an integrated suite vs. one that’s unified. Read this whitepaper to learn more. Sponsored by: Patheon, part of Thermo Fisher Scientific Read this whitepaper to learn how the biologics market is quickly evolving and how these changes pose several risks to a molecule’s success. Sponsored by: Coupa Software Learn how Becton Dickinson implemented Coupa to create an easy-to-use purchase to pay process that increased efficiency across the organization. Sponsored by: Almac Diagnostic Services, part of the Almac Group Download the whitepaper to learn more. Sponsored by: Reprints Desk, Inc. Learn how to fast-track your research workflows! Sponsored by: Veeva Industry Research: Read the 2018 Unified Clinical Operations Report to find out how pharmas and CROs are evolving clinical trial processes. Sponsored by: Applied BioMath This on-demand webinar introduces a quantitative systems pharmacology (QSP) model of targeted anabolic growth factors for intra-articular injection for the treatment of diseased joints. Sponsored by: Oracle Health Sciences New research reveals more than 50% of clinical data management professionals surveyed, are not confident in the quality and completeness of their clinical trial data. Sponsored by: Outer Edge Technology Outer Edge Technology specializes in designing and managing regulated cloud-based infrastructures for the Life Sciences Industry – typically leveraging the AWS and Microsoft Azure platforms. Sponsored by: Biotech Primer The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry. Drug Approval, Manufacturing Quality & Regulation 2018 | Online FierceBiotech Executive Breakfast at the J.P. Morgan Healthcare Conference 2019 January 8, 2019 | The Fairmont Hotel | San Francisco, CA Phacilitate Leaders World 2019 January 22-25, 2019 I Hyatt Regency, Miami 2019 Bridging Clinical Research & Clinical Health Care Collaborative March 4–5, 2019 | National Academy of Sciences | Washington, D.C. Asia-Pacific Compliance Training for Life Sciences Professionals March 4-7, 2019 | Singapore PEGS: The Essential Protein Engineering Summit April 8 – 12 | Boston, MA | 