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November 28, 2018

Today's Rundown

Featured Story

Genentech snaps up NASH-focused Jecure Therapeutics

Companies have been piling into the nonalcoholic steatohepatitis (NASH) space lately, and Genentech is no exception. The biotech acquired Jecure Therapeutics and its stable of NLRP3 inhibitors for an undisclosed amount.

Top Stories

Chinese researcher claims to have made the first CRISPR-edited babies

A Chinese researcher has claimed to be the first to use CRISPR gene-editing tools on live, implanted human embryos, resulting in the birth of twin girls and swift international backlash over the ethics of the procedure.

Drug-screening Kronos Bio nets new chief business officer from Regeneron to develop pharma partnerships

Kronos Bio, a member of this year’s Fierce 15, has snagged Regeneron Pharmaceuticals’ executive director of business development, Philip Gutry, to serve as its new chief business officer—tasking him with managing the company’s clinical alliances and expanding its pipeline.

[Sponsored] Minimal Residual Disease: Application in Blood Cancers

A diagnosis of chronic lymphocytic leukemia (CLL) can mean a long road with many twists and turns as patients try to achieve long-term remission from this chronic, complex and progressive form of blood cancer.

Hookipa tasks DarwinHealth with finding shared tumor antigens

Hookipa Pharma has teamed up with DarwinHealth to identify shared self-antigens for multiple tumor subtypes. The collaboration is expected to yield antigens with validated immunogenicity that Hookipa can use as the basis for immunotherapies.

Prometic secures $50M stock sale option to ease cash crunch

Prometic Life Sciences has entered into an agreement to sell up to $50 million in stock over the next 16 months. The agreement gives Prometic a way to trickle cash into its bank account while working to escape its current financial pressures.

Vedanta pockets $12M from Johnson & Johnson on start of microbiome drug trial

Vedanta Biosciences’ three-year-old collaboration with Johnson & Johnson on microbiome therapies has moved to the clinical stage, triggering a $12 million milestone payment.

Roche launches new TRK assay, as Bayer, Loxo get FDA nod for pancancer drug

Roche launched a new automated in vitro diagnostic to detect tropomyosin receptor kinase proteins in cancer, which the company hopes will have potential use in a range of solid tumor types and site-agnostic targeted therapies—such as Bayer and Loxo Oncology’s newly approved pancancer drug, Vitrakvi.

Enrollment Showcase

BioBasics Dec. 5-6

BioBasics is an intensive two-day course starting with a review of the healthcare sectors and the scientific concepts required for understanding the biopharma industry, then delves into the cause of genetic and infectious disease, diagnostics and strategies used to mitigate disease and finally the latest innovations in biopharma are explained. Register today!

Resources

[Webinar] Becton Dickinson’s Digital P2P Solution Simplifies Spend Management

Learn how Becton Dickinson implemented Coupa to create an easy-to-use purchase to pay process that increased efficiency across the organization.

[Whitepaper] Evaluation of the claraT Total mRNA report in an RNA- Sequencing dataset from malignant melanoma cancer patients treated with Ipilimumab

Download the whitepaper to learn more.

[Whitepaper] Putting the Researcher in the Driver’s Seat

Learn how to fast-track your research workflows!

[Report] Clinical Operations Report: Learn the Top Industrywide Priorities

Industry Research: Read the 2018 Unified Clinical Operations Report to find out how pharmas and CROs are evolving clinical trial processes.

[Webinar] QSP Approaches to Determine Best in Class Properties for Targeted Anabolic Growth Factor to Arthritic Joints

This on-demand webinar introduces a quantitative systems pharmacology (QSP) model of targeted anabolic growth factors for intra-articular injection for the treatment of diseased joints.

[Research Report] Challenges And Opportunities In Clinical Data Management

New research reveals more than 50% of clinical data management professionals surveyed, are not confident in the quality and completeness of their clinical trial data.

[Whitepaper] Migraine Treatment and Calcitonin Gene-Related Peptide Inhibitors: Real-World EHR Case Study

New Case Study – Leveraging Real-World Evidence From EHR to Assess Migraine Management

[Whitepaper] The Future of Cell & Gene Therapy

What does data tell us about the future of cell & gene therapy?

[Whitepaper] Choosing the Best Sterile Dosage Form for Your Clinical Supply Needs

Download the whitepaper to learn more.

[Whitepaper] Why Life Sciences Companies Leverage Managed Regulated Infrastructures

Outer Edge Technology specializes in designing and managing regulated cloud-based infrastructures for the Life Sciences Industry – typically leveraging the AWS and Microsoft Azure platforms.

[Infographic] Accelerate Your Early Drug Delivery Journey

In the United States, it takes an average of 12 years for an experimental drug to travel from the laboratory to a patient’s medicine cabinet. The average cost to research and develop a successful drug is approximately $2.6 billion.

[Workshop] Smart Drug Development & Design from Candidate to Phase I

Today’s scientists are under significant time pressure to accelerate their compound from discovery to the clinic. Such pressure can often lead research organizations to adopt short-term thinking and overlook the downstream realities of drug development.

[Executive Summary] From Candidate to Clinic

What is the fastest way to success? It is critical that drug developers execute several elements related to planning, investment, and understanding of the risks, risk tolerance, and pitfalls inherent in the drug development program.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

[eLearning] BIOAVAILABILITY 101

Develop a basic understanding of principles and concepts of bioavailability of oral drugs.

Events

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