Today's Rundown FDA hits Zafgen’s beloranib successor with clinical hold After gene therapy pivot, Axovant bolsters its executive ranks Vir starts trial of RNAi drug for hep B seeking functional cure [Sponsored] Minimal Residual Disease: Application in Blood Cancers Vectura cans VR475 after it fails phase 3 asthma test Illumina leads €16M round for digital PCR firm Stilla Technologies Featured Story | | | Monday, November 26, 2018 The FDA has placed a clinical hold on Zafgen’s ZGN-1061. Zafgen suffered the blow after failing to allay the FDA’s concerns that ZGN-1061 will face similar cardiovascular safety problems to its predecessor, beloranib. |
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Top Stories Monday, November 26, 2018 After switching its focus midyear from Alzheimer’s disease to gene therapy, Axovant is appointing a slew of new executives, including a pair of Novartis alums and several biotech veterans, to posts ranging from clinical development to commercial operations. Monday, November 26, 2018 Vir Biotechnology has started a phase 1/2 trial of its gene-silencing drug for hepatitis B virus, the first clinical candidate from its partnership with Alnylam Pharmaceuticals. Monday, November 26, 2018 A diagnosis of chronic lymphocytic leukemia (CLL) can mean a long road with many twists and turns as patients try to achieve long-term remission from this chronic, complex and progressive form of blood cancer. Monday, November 26, 2018 A phase 3 trial of Vectura’s VR475 in patients with severe uncontrolled asthma has missed its primary endpoint. The blow prompted Vectura to halt work on the nebulized formulation of the budesonide. Monday, November 26, 2018 Illumina’s venture arm led a €16 million ($18 million) series A round for Stilla Technologies, a Paris-based developer of digital PCR solutions for genetic analysis. | This week's sponsor is Johnson & Johnson Innovation. | | | |
Enrollment Showcase | | | Sponsored by: Biotech Primer BioBasics is an intensive two-day course starting with a review of the healthcare sectors and the scientific concepts required for understanding the biopharma industry, then delves into the cause of genetic and infectious disease, diagnostics and strategies used to mitigate disease and finally the latest innovations in biopharma are explained. Register today! |
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