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November 16, 2018

Welcome to FierceLifeSci Weekly Digest, your roundup of the biggest and most popular stories from each of our publications.

Featured Story

Moderna shoots for $500M IPO, the biggest in biotech history

Two months after rumblings emerged that Moderna Therapeutics was prepping what would be biotech’s biggest IPO, the company has come through, filing on Friday to raise $500 million.

Top Stories Of The Week

Special Report—The top 10 cancer drug makers of 2024

At first glance, the list of cancer drug makers predicted to head the field by 2024 may not look so different from the list of top-selling cancer drug makers in 2017. But the lists themselves don’t tell the whole story.

Sandoz recalls losartan products that contain impurity

Months after world regulators first discovered impurities in the ingredient of a Chinese drugmaker, tainted drugs continue to show up in the U.S. supply. This time, it involves losartan blood pressure drugs from Sandoz.

GSK pancreatic cancer drug heads to phase 1 combo with Merck's Keytruda after positive mouse trial

GlaxoSmithKline’s experimental drug GSK095, a RIP1 inhibitor, is designed to work in tandem with checkpoint-inhibiting medicines in the hopes of empowering the immune system to launch a more aggressive attack against tumors than it does with checkpoint inhibitors alone. Early results from a trial of a related GSK drug suggest that combining the drug with Merck's blockbuster Keytruda holds promise in treating pancreatic cancer.

Roivant raises $200M, at $7B valuation, to add to startup roster

Roivant Sciences has raised $200 million to roll out another round of startups. The financing, which comes 15 months after Roivant raised $1.1 billion, is tied to a $7 billion valuation for the fast-growing biotech umbrella organization.

Express Scripts ramps up list-price pressure with newfangled 'Flex' formulary

Express Scripts is rolling out a new formulary to assist drugmakers with lowering list prices, starting with Gilead's new hepatitis C authorized generics.

Lured by high demand, Korean wholesaler smuggled Novo’s obesity drug Saxenda into China

Anti-obesity drug Saxenda has been one of Novo Nordisk’s key growth drivers lately—and apparently, a Korean wholesaler noticed. The pharmaceutical middleman allegedly smuggled the popular drug into China, where it’s not yet approved.

Google to retake DeepMind’s AI healthcare unit as it moves toward a cohesive strategy

Days after poaching a health system executive to pull together its disparate healthcare ventures, Google moved to reabsorb DeepMind’s health business, including those behind its mobile app for doctors and nurses.

Amarin’s Vascepa cuts heart risks in key trial, but placebo noise fuels controversy

Some expecting a home-run win from Amarin’s heart drug Vascepa in cardiovascular benefits might now feel less excited. As detailed data showed, the drug did cut heart risks significantly, but the choice of placebo has cast doubt on the otherwise stellar results.

Parexel links with Medidata’s Shyft to boost its real-world data offering for clients

Biopharma services provider Parexel is linking up with Medidata’s Shyft Analytics to boost its real-world evidence offering for biopharma and medical device clients.

Merck quadruples Gardasil supply in China contract but still might not meet full demand

Facing buoyant demand in China for its HPV vaccines, Merck & Co. has promised almost quadrupled supply in the coming years in a renewed contract with a local distributor. But that still might not be enough to meet the full demand there.

Resources

[Report] Clinical Operations Report: Learn the Top Industrywide Priorities

Industry Research: Read the 2018 Unified Clinical Operations Report to find out how pharmas and CROs are evolving clinical trial processes.

[Research Report] Challenges And Opportunities In Clinical Data Management

New research reveals more than 50% of clinical data management professionals surveyed, are not confident in the quality and completeness of their clinical trial data.

[Whitepaper] Migraine Treatment and Calcitonin Gene-Related Peptide Inhibitors: Real-World EHR Case Study

New Case Study – Leveraging Real-World Evidence From EHR to Assess Migraine Management

[Whitepaper] The Future of Cell & Gene Therapy

What does data tell us about the future of cell & gene therapy?

[Whitepaper] Choosing the Best Sterile Dosage Form for Your Clinical Supply Needs

Download the whitepaper to learn more.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

[eLearning] BIOAVAILABILITY 101

Develop a basic understanding of principles and concepts of bioavailability of oral drugs.

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