AstraZeneca targets severe COVID-19 patients for antibody therapy despite Regeneron, Lilly setbacks What could an aducanumab approval mean for future Alzheimer's R&D? Humanigen links drug to improvements in severe COVID-19 patients Sponsored: Best Practices for Research Sites: Effectively Using Patient Recruitment Advertising Dollars Assembly flop sees it pivot from curative to chronic hep B focus Bristol Myers Squibb, fueled by COVID-19 and social justice movement, ramps up diversity efforts in clinical trials Obesity-related gene that controls cravings and exercise motivation in mice could inspire new therapies FiercePharmaAsia—AstraZeneca's China slowdown; Novartis' Asia CAR-T site; Clover's COVID-19 funding Chutes & Ladders—Novartis alums Jimenez, Fishman unveil their next act Featured Story | By Nick Paul Taylor AstraZeneca has talked up the prospects of its anti-SARS-CoV-2 antibody working in severe COVID-19 patients despite rival assets from Eli Lilly and Regeneron failing in that population. Mene Pangalos, an AstraZeneca EVP, made the comments while sharing news the antibody is set to start a prophylaxis study next week. read more |
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Top Stories By Amirah Al Idrus Experts and industry watchers fully expect the FDA to approve Biogen’s controversial Alzheimer’s drug aducanumab—but not because it’s a game changer. In the words of one analyst, aducanumab won’t get the agency’s nod because its data are strong, but rather “in spite of the quality” of those data. read more By Nick Paul Taylor Humanigen has estimated its anti-GM-CSF antibody caused 37% more recoveries than standard of care in hospitalized COVID-19 patients. The data remain blinded, but Humanigen calculated the effect of the drug based on the changes to enrollment requested by the data safety monitoring board. read more Sponsored By: WCG Are you looking to optimize your site’s patient recruitment advertising dollars? WCG’s experienced team of patient recruitment experts can help your site efficiently use your advertising funds by creating customized recruitment campaigns for any of your studies, and we’ve also curated a list of best practices to ensure your spend sees the best ROI. read more By Ben Adams Assembly Bio was hoping its experimental hepatitis B drug could be a functioning cure for the viral liver disease, but a midstage flop has seen the biotech rethink this path in the near term. read more By Amirah Al Idrus Bristol Myers Squibb was already working on a plan to boost diversity in clinical trials, but the events of 2020—namely a pandemic that disproportionately affects minorities and a social justice movement reignited by the murder of George Floyd—ramped up its efforts. read more By Arlene Weintraub Could a single gene reduce our craving for sugary foods while at the same time increasing our desire to exercise? NIH researchers reported that knocking out a gene called Prkar2a in mice caused the animals to cut their consumption of high-fat foods and increased their motivation to exercise. read more By Angus Liu AstraZeneca's sales suffered in the third quarter because of a COVID-19-related slowdown of Pulmicort in China. Novartis established its first CAR-T facility in Asia. China's Clover Biopharma won a $258 million grant from CEPI for its COVID-19 vaccine work. And more. read more By Conor Hale Novartis alums Jimenez, Fishman unveil their next act, Deep Genomics nabs a CBO from Synlogics, and Santhera's CMO hits the exit. read more Resources Sponsored By: Medidata Responding to site challenges. Approaching virtualization. Leveraging real-time data. Medidata shares 8 parameters to implement your virtualization strategy during COVID-19 and beyond. Download Now. Sponsored By: WCG Need additional site resources for your current or upcoming clinical trial? 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