| | Key considerations for running rare oncology trials. Recruiting patients with specific biomarkers and genetic characteristics can be difficult for any clinical trial, even more so, for rare oncology trials. Join Synteract’s oncology and rare experts as they tackle these challenges in our next webinar, Rare Cancers: Special Considerations for Complex Clinical Studies. |
AstraZeneca tipped to restart COVID-19 vaccine trial this week: report Biogen finally culls MS dud opicinumab, adds SMA gene therapy to the garbage heap CRISPR stock slides as CAR-T death overshadows signs of efficacy GSK sees 'robust immune response' from RSV vaccine hopefuls Anatomy of a deal: How Myokardia got BMS to bump up its buyout to $13B SparingVision raises €44.5M to develop mutation-agnostic gene therapy BridgeBio, with 21 programs underway, keeps an eye out for more prospects in new academic deals InCarda raises $30M to reimagine afib treatment with drug-device combo One pandemic, $2 billion, 3 months: Top COVID-19 player Thermo Fisher posts hefty Q3 revenue Inhaled antibody drug for COVID-19 clears coronavirus in animals Featured Story | By Nick Paul Taylor AstraZeneca could resume the U.S. clinical trial of its COVID-19 vaccine this week, according to a Reuters report. The trial has been paused since early September while the FDA reviews the safety of the vaccine in light of a reported case of a rare spinal inflammatory disorder in the wider program. read more |
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Top Stories By Ben Adams Biogen is cutting its experimental multiple sclerosis drug opicinumab as well as an spinal muscular atrophy candidate amid a third-quarter clear-out. read more By Nick Paul Taylor One of the first 11 patients to receive CRISPR Therapeutics’ anti-CD19 allogeneic CAR-T cell therapy has died. The patient was hospitalized with febrile neutropenia in the weeks after receiving the drug and died 52 days post-treatment with the CAR-T therapy. read more By Ben Adams Cold viruses often don’t get much of a look when it comes to R&D; they are annoyances, but ones that usually make us feel miserable for a few days, then clear up. read more By Amirah Al Idrus MyoKardia wasn’t looking for a buyout when it started discussing potential partnerships with Bristol Myers Squibb last year. But when the Big Pharma came knocking in September to ink a quick acquisition, the biotech’s executives made sure they wrung as much as they could out of the deal. read more By Nick Paul Taylor SparingVision has raised €44.5 million ($52.5 million) to develop its mutation-agnostic gene therapy treatment for retinitis pigmentosa (RP). The financing positions SparingVision to fund clinical trials of an AAV gene therapy that could stop vision deterioration in the 2 million RP patients. read more By Amirah Al Idrus BridgeBio Pharma may be gearing up for its first approvals, but it’s not taking its foot off the gas in early-stage research. The company inked a pair of R&D deals with the University of Colorado and the Salk Institute—its third and fourth academic collaborations of the year. read more By Amy Sokolow The drug that treats atrial fibrillation, flecainide, has been around since the '80s. Grace Colón, CEO of InCarda, thinks it needs a face-lift. With a $30 million initial round of series C financing led by Innoviva and existing investors Deerfield Management, HealthCap and Morningside Ventures, InCardia is hoping to make flecainide available as an at-home inhalable treatment. read more By Conor Hale As a top producer of diagnostic test kits, laboratory hardware and supplies, Thermo Fisher Scientific has been a major player in the global response to the COVID-19 pandemic almost from the start—and now, the company has shown exactly how major. read more By Angus Liu An inhaled neutralizing antibody cleared the novel coronavirus from infected hamsters at a far lower dose compared with other experimental monoclonal antibodies. The drug is now being developed by Aridis Pharmaceuticals and could offer a self-administered option for COVID-19 if it succeeds in human testing. read more Resources Sponsored By: Paysign Download the whitepaper for a solution designed to connect manufacturers, pharmacists, and patients. 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