To view this email as a web page, click here

   Home

Subscribe

Advertise

 

 

 

 

October 07, 2019___

Today's Rundown

Featured Story

Amid C-suite shake-up, Gilead nabs Genentech exec as new CMO

After a series of major exits from its C-suite last year and this year including the exit of Chief Medical Officer Andrew Cheng last fall, Gilead now has a new CMO as it also rejigs its R&D reporting line.

Top Stories

After leadership shuffle, Akcea hands heart drug to Pfizer for $250M

After an unexpected game of executive musical chairs, Akcea Therapeutics has inked a deal with a potential rival. For $250 million upfront, Akcea is licensing an antisense therapy to Pfizer for “certain cardiovascular and metabolic diseases.”

Nobel Prize in medicine goes to oxygen sensing research 

Researchers who advanced understanding of how cells sense and adapt to oxygen availability have won the 2019 Nobel Prize in physiology or medicine. The research could inform development of treatments for diseases including anemia, cancer and stroke.

[Sponsored] Thwarting Subjectivity in Clinical Trials

A clinical trial is a measurement system, but too often, we fail to calibrate the most significant of measurement instruments: trial participants.

Early readout from small NGM study shows NASH drug hits liver fat, but shares fall

Expectations for nonalcoholic steatohepatitis are still sky-high—some see tens of billions for any drug that gets it right at peak—but the reality of clinical trials assessing fatty liver assets has been a lot murkier.

Atlas unveils RNA-editing Korro Bio helmed by Nessan Bermingham

Nearly two years after handing over the reins of Intellia Therapeutics, Nessan Bermingham has landed in the CEO chair of another Atlas company: Korro Bio, which is working on RNA-modifying treatments based on nucleotide deamination.

Oxford spinout MiroBio bags £27M for autoimmune R&D

MiroBio has raised £27 million ($33 million) to fund research into immune cell regulation. The series A round will bankroll efforts to develop antibodies that treat autoimmune diseases by stimulating specific immune cell signals.

U.K. launches trial of Boston Pharma's resistance-busting combo in triple-negative breast cancer

A drug from Boston Pharmaceuticals called BOS172722 causes cancer cells to divide too rapidly and die. The medicine combined with chemo was effective in mouse models of triple-negative breast cancer and is being tested in a phase 1 trial in the U.K.

Resources

[Whitepaper] The Next Generation of Trial Master File Systems

Simplified filing, improved oversight, audit readiness: is your eTMF system delivering best-in-class benefits?

[Whitepaper] Implementing On-Dose Authentication Technologies for Solid Dose Drug Products

Learn about how you better manage product authentication and battle drug counterfeiting with innovative solutions.

[Whitepaper] Cortellis Q2 2019 M&A report

Download this report for full details of Life sciences M&As in the second quarter of 2019 with notes and trends.

[Whitepaper] SOAR™ Model Manages Data From Source to Submission

Find out how it leverages real-world data and novel IntElligo Research Stack™ technology to help researchers battle rising costs, cumbersome processes, and stagnant participation — bridging the gap between research and care.

[Whitepaper] Successful Clinical Trials in the Era of Genetics-based Medicine

Download this complimentary guide paper that explores key strategies for a successful genetics-informed clinical trial.

[Whitepaper] Best Practices for Incorporating Real World Imaging Data into RWE Programs

The time has finally come when medical imaging can be effectively utilized into the RWE process. Read the whitepaper on the best practices for incorporating Real World Imaging.™

[Whitepaper] Synthesizing Success: Six Principles for Getting Pharmaceutical Development Right from the Start

Is your API development on track?

[Whitepaper] Advanced Analytical Approaches for Accelerated Development of Gene Therapy Products

Download the White Paper and learn how detailed characterization can guide successful development of gene therapy products.

[Whitepaper] Webinar Benchmarks Report for Life Sciences 2019

Compare digital program performance and audience engagement among your life sciences peers.

[Webinar] Clinically Integrated Networks: A Growing Disruptor in American Healthcare

Clinically Integrated Networks are vehicles for powerful IDNs to extend their influence into the physician sector and play a key role for IDNs trying to pave a path to becoming a self-contained healthcare ecosystem.

[Whitepaper] Fail Fast. Succeed Faster.

Slashing your R&D costs is easier than you think.

[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Whitepaper] Understanding Precision Medicine in Oncology

White paper providing an overview of precision medicine in oncology, as well as a look ahead at future developments and keys to success for pharmaceutical and diagnostics companies.

[Article] Why Market Leaders Outsource IT Requirements For A Competitive Edge

Find out how outsourcing your IT requirements enhances the bottom line while creating strategic advantage.

[Whitepaper] From Complex to Controlled: Advanced Data Management Strategies for Advanced Therapies

Developing a cell therapy, gene therapy, or personalized cancer vaccine? Modern data management makes a critical difference in operational and regulatory outcomes. This whitepaper will help your team leverage the latest data strategies for success.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events