Amgen, J&J most vulnerable to IRA: Moody’s

Today’s Big News

Sep 7, 2023

Roche hits FDA delay with subcutaneous version of Tecentriq amid manufacturing process changes  


Philips reaches first settlement in class-action CPAP lawsuit  


Amgen, J&J most vulnerable to IRA price negotiations in 2026: Moody's 


Roche's $310M metabolic bet pays off as Alnylam med reduces blood pressure in phase 2 


Zimmer Biomet doles out a flurry of executive promotions after CEO switch-up 


Are DACs the new ADCs? Seagen pays Nurix $60M to find out 

 

Featured

Roche hits FDA delay with subcutaneous version of Tecentriq amid manufacturing process changes

Roche may not receive the FDA's decision on a subcutaneous version of its cancer immunotherapy Tecentriq on time thanks to the agency's requirement for changes to the drug's manufacturing process.
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Top Stories

Philips reaches first settlement in class-action CPAP lawsuit

The first settlement covers only economic loss claims. Hundreds of personal injury and wrongful death claims still have yet to be tied off.

Amgen, J&J most vulnerable to IRA price negotiations in 2026: Moody's

Now that the CMS has revealed its list of the first 10 drugs subject to Medicare price negotiations under the Inflation Reduction Act, it’s time to consider the financial implications for affected companies.

Roche's $310M metabolic bet pays off as Alnylam med reduces blood pressure in phase 2

Roche’s $310 million splash into the metabolic therapy pool two months ago already appears to be paying off, with its Alnylam-partnered hypertension med reducing blood pressure in a phase 2 trial.

Zimmer Biomet doles out a flurry of executive promotions after CEO switch-up

In less than a month, Zimmer Biomet’s executive team has gotten quite the makeover.

Are DACs the new ADCs? Seagen pays Nurix $60M to find out

What do you get when you combine the established cancer modality of antibody-drug conjugation with targeted protein degradation? An intriguing new class of antibody drugs called degrader-antibody conjugates—and Seagen is keen to get in on the ground floor.

Boston Scientific claims FDA approval for latest Watchman heart plug implant

Compared to its predecessor, the Watchman FLX Pro features a new polymer coating designed to assist in the natural healing process following the procedure.

Eli Lilly hops aboard for Mariana Oncology's $175M series B, radiopharmaceuticals mission

Investors have reached deep into their pocketbooks for Mariana Oncology’s series B financing, with Eli Lilly coming aboard for the oversubscribed $175 million round aimed at making waves in radiopharmaceutical development.  

Novo Nordisk teams up with Harvard, Broad Institute on diabetes and cardiac fibrosis

Novo Nordisk will collaborate with Harvard and the Broad Institute of Massachusetts Institute of Technology to develop three new programs over the next three years to tackle diabetes and cardiac fibrosis.

GSK could face disruptions at 2 sites from possible UK contractor strike, union says

Engineering construction workers—who help repair and maintain pharmaceutical plants, oil refineries and more—are weighing whether to strike in the United Kingdom. The potential industrial action, centered on a pay dispute, could affect two GSK sites. But it's still too early to say whether the contractors will actually strike.
 

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Transitioning from using RUO to cGMP chemicals for clinical trials

By 2030, the global demand for biologics is projected to grow at a CAGR of 8.7% and the challenges, risks, and costs of bringing large molecule products to market are growing exponentially.
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Biotech in the UK: Mapping the Runway to Success

15 biotech executives from the Cambridge area discuss the current biotech landscape, as well as challenges, opportunities, and best practices for emerging biotech companies seeking success in the UK and beyond.
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Plan for success with your process liquid and buffer preparation

Learn how process liquids and buffers impact your total cost of ownership (TCO) and how outsourcing can revolutionize your approach, ensuring quality standards and improving productivity.
 

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