Today's Rundown After midphase flop, Pfizer taps Cytoo for help identifying DMD targets Akcea lays off 10% of staff following volanesorsen rejection Elevian set up to pursue disputed approach to aging diseases Using genomics and machine learning to predict aneurysm risk EuroBiotech Report—Teva dumps laquinimod, Gilead-Galapagos, GV-Evox, Abivax data and ProQR FiercePharmaAsia—Aurobindo’s $1B Sandoz buy; ex-GSK scientist guilty plea; Chi-Med’s Elunate win Chutes & Ladders—Sean Harper and Beth Seidenberg unite to run $320M VC fund Featured Story | | | Friday, September 7, 2018 Pfizer has teamed up with Cytoo to work on a Duchenne muscular dystrophy (DMD) target discovery platform. The early-stage alliance comes a week after Pfizer halted development of domagrozumab in DMD because of lackluster midphase data. |
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| This week's sponsor is Trianni. | | | |
Top Stories Friday, September 7, 2018 Akcea Therapeutics is laying off 10% of its workforce. The cuts come 10 days after the FDA rejected a filing for approval of volanesorsen and left Akcea with little use for the team it built up to promote the ultrarare lipid disorder drug. Friday, September 7, 2018 New startup Elevian has launched with $5.5 million in backing to develop drugs based on GDF11, a Harvard University-discovered protein that it says is linked to age-related diseases. Friday, September 7, 2018 Stanford scientists used machine learning to identify mutational patterns in 60 genes that raise the risk of abdominal aortic aneurysm, an irreversible disorder in which the body’s main artery gradually enlarges. Friday, September 7, 2018 In this week's EuroBiotech Report, Teva dumps laquinimod, Galapagos wobbles amid safety scare, GV backs Evox and more. Friday, September 7, 2018 Novartis is offloading some U.S. generics and dermatology business to Aurobindo for $1 billion; a former GlaxoSmithKline scientist has pleaded guilty to stealing trade secrets to benefit her Chinese company; Eli Lilly and Chi-Med's Elunate is the first Chinese-made drug to win a major cancer nod; and more. Friday, September 7, 2018 Sean Harper and Beth Seidenberg unite to run $320 million VC fund; Agios crowns Jackie Fouse as CEO; hospital-backed Civica Rx nabs Amgen veteran as CEO; and Lilly hands oncology baton to R&D executive Anne White. Those moves plus more hirings, firings and retirings throughout the industry. | This week's sponsor is ExL Events. | | Discount price rate ends 9/7 for the Collaborations Addressing Vulnerable Populations (CAVP) Forum!
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