Novo Nordisk ponies up $1.1B for Forma in effort to shape up sickle cell disease market Novartis R&D chief Bradner bids adieu to the Swiss Big Pharma Finch axes more than a third of its workforce days after Takeda clips its fiscal wings AnaptysBio's HARP plays dud note, prompting rethink of imsidolimab strategy As activist investor ratchets up pressure, Mereo makes more cuts to extend cash runway into 2025 Uncovering a link between lung cancer and chronic pain—and a druggable pathway for both Sanofi spinoff EUROAPI hits the ground running with double-digit growth in the first half One protein, many cancers: Immatics finds a multi-tumor target for adoptive T-cell therapies AstraZeneca scores injunction to temporarily halt former exec's start at crosstown rival GSK Vibrant Gastro passes vibrating constipation pill through FDA review Backlash against CVS, Walgreens raises questions about role of retail in post-Dobbs world Featured Story | By Gabrielle Masson Novo Nordisk is handing over $1.1 billion in cash to buy Forma Therapeutics in hopes that the clinical-stage biotech’s assets will help build a leading portfolio in sickle cell disease. read more |
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Top Stories By Max Bayer Novartis' head of R&D Jay Bradner is stepping down after seven years at the helm, with plans to pursue new ventures. For his replacement, the company tapped Merck executive Fiona Marshall, who will take over in November. read more By Max Bayer Finch is cutting 37% of its workforce days after Takeda returned two preclinical assets back to the microbiome-focused biotech. The company is also pausing clinical trial plans of its treatment for autism spectrum disorder. read more By Nick Paul Taylor AnaptysBio’s stuttering effort to rebuild its pipeline around imsidolimab has hit another setback. After flopping in palmoplantar pustulosis and acne, the anti-IL-36 receptor antagonist has failed to move the needle in the chronic skin disease hidradenitis suppurativa, leading the biotech to stop work on one indication and plan to out-license the asset. read more By Nick Paul Taylor Mereo BioPharma, under pressure from an activist investor, has reduced its head count to stretch its cash runway out into the second quarter of 2025. The biotech disclosed the cuts in a rebuttal to Rubric Capital Management’s “low-risk strategy” for unlocking the value of its assets while preserving cash. read more By Gabrielle Masson Scientists revealed a link between chronic pain and lung cancer—a link that also offers a potentially druggable pathway for both conditions, according to new research conducted in mouse models. read more By Fraiser Kansteiner Just a few short months after liftoff, Sanofi’s drug ingredients spinoff EUROAPI has started to show its promise as a standalone company. For the first half of 2022, the company generated 483.8 million euros (about $483.2 million) in revenue. read more By Helen Floersh Despite the hype around adoptive T-cell therapies, it’s still a challenge to find therapeutic targets that are consistent across tumor types and aren’t expressed in healthy cells. Now, a team of scientists working with immunotherapy drug development biotech Immatics has identified an antigen component that checks both of those boxes. read more By Fraiser Kansteiner Just hours before outgoing AstraZeneca executive Chris Sheldon was set to take up his post at crosstown rival GSK, a judge has ordered a temporary injunction. read more By Andrea Park Fresh off reporting the promising results of a phase 3 study of its constipation relief device, Vibrant Gastro is keeping things moving. read more By Annie Burky Messages on the popular social media site accused the retail pharmacy of “putting politics over patients" by refusing to fill a prescription for non-abortion related care. 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