Genentech, Sangamo sign neuro pact

Today’s Big News

Aug 6, 2024

Merck advances lung cancer attack, pocketing $170M from Daiichi and plotting ADC-trispecific combo


BioMarin continues pipeline clearout by halting preclinical gene therapy for heart condition


Sangamo secures $50M upfront in neurodegenerative pact with Roche's Genentech


Ultimovacs cancer vaccine goes 0 for 3, shuffling into last chance saloon with latest failure


Eisai plants molecular glue SEED with $1.5B biobucks deal in neuro, oncology


Ex-Pfizer drug reduces osteoarthritis pain in British biotech's phase 2 study


With ties to Arie Belldegrun’s Bellco, credit firm Symbiotic Capital unveils with $600M

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Featured

Merck advances lung cancer attack, pocketing $170M from Daiichi and plotting ADC-trispecific combo

Merck & Co. has quickly recouped some of the costs of its Harpoon Therapeutics buyout, pulling in $170 million upfront by incorporating the lead candidate into a co-development deal with Daiichi Sankyo.
 

Top Stories

BioMarin continues pipeline clearout by halting preclinical gene therapy for heart condition

After BioMarin conducted a spring clean of its pipeline in April, the company has decided that it also needs to offload a preclinical gene therapy for a condition that causes heart muscles to thicken.

Sangamo secures $50M upfront in neurodegenerative pact with Roche's Genentech

After Biogen and Novartis walked away from partnerships with Sangamo Therapeutics in 2023, the biotech has secured a pact with Roche’s Genentech working on intravenous genomic medicines for neurodegenerative diseases.

Ultimovacs cancer vaccine goes 0 for 3, shuffling into last chance saloon with latest failure

Ultimovacs’ cancer vaccine UV1 has failed yet another midphase clinical trial. The third flop, this time in head and neck cancer, leaves UV1 with one shot at salvation before the Norwegian biotech reaches the end of its cash runway.

Eisai plants molecular glue SEED with $1.5B biobucks deal in neuro, oncology

Big Pharmas remain stuck to the idea of molecular glue degraders. The latest company to see an opportunity is Japan’s Eisai, which has signed a $1.5 billion biobucks pact with SEED Therapeutics for undisclosed neurodegeneration and oncology targets.

Ex-Pfizer drug reduces osteoarthritis pain in British biotech's phase 2 study

Levicept arose from the metaphorical ashes of Pfizer’s former R&D campus in the U.K. Now, the biotech has scored a phase 2 win for an osteoarthritis drug that can also be traced back to the Big Pharma.

With ties to Arie Belldegrun's Bellco, credit firm Symbiotic Capital unveils with $600M

A new global life science credit firm, dubbed Symbiotic Capital, has raised more than $600 million. The organization will deliver credit solutions to companies across biotech, medtech, synthetic biology and other healthcare sectors.

Novartis and Viatris sued by estate of Henrietta Lacks, whose cells were extracted for research in 1951

The family of a Baltimore woman whose cells were extracted for medical research without her consent more than 70 years ago has filed another lawsuit against drugmakers that allegedly profited from the discoveries they made using her genetic material. The estate has sued Novartis and Viatris, seeking a jury trial and the “full amount” of profits obtained through their use of the “stolen” cells.

TPG tops up funds to $580M for investments across the life sciences spectrum

Asset manager TPG, which has supported biotechs such as Sionna Therapeutics and Santa Ana Bio, has topped up its Life Science Innovations fund, bringing total capital raised for the effort to $580 million.

Fierce Biotech Fundraising Tracker '24: Red Queen reveals $55M launch; MBX Bio bags $63M series C

Welcome to Fierce Biotech's Fundraising Tracker, 2024's version.

3 years in, Genentech's Site Alliance enrolls underrepresented patients 2 times faster than other sites

Three years since founding Site Alliance in 2021, Genentech is now sharing data showing sites in the alliance enroll more Black and Hispanic/Latinx patients than other sites in the same studies and enroll these underrepresented groups about two times faster.

Mallinckrodt to sell Therakos business unit to CVC Capital for $925M

Special pharmaceutical company Mallinckrodt is selling its photopheresis business, Therakos, to CVC Capital Partners for $925 million.

Bayer's transformation gathers steam as its job cut total reaches 3,200 this year

Bayer’s transformation under CEO Bill Anderson has picked up momentum. In reporting second-quarter earnings on Tuesday, the company revealed it has cut 3,200 jobs since the start of this year. That number includes the 1,500 staffers the company said it laid off in the first quarter.

Hims & Hers projects 2024 revenue to hit $1.37B buoyed by demand for weight loss drugs

Hims & Hers launched a virtual weight management program in December, adding compounded GLP-1 medications in May, and that investment is quickly paying off.
 
Fierce podcasts

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What 'The Next Berlin Patient' and a PrEP’s 100% efficacy mean for HIV drug development

This week on “The Top Line,” we dive into two studies in HIV research that were presented at the 25th International AIDS Conference in Germany.
 

Resources

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Launching a Product in Europe: Understanding Supply Chain Cost Drivers

This paper explores the costs of setting up a supply chain in Europe for a new biopharma therapy. It outlines key cost drivers & the various levers decision makers can use to affect those costs.
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Efficient-Pro Medium and Feed 1 enable rapid and seamless upstream process development and scale-up for CHO-K1 cells

Download the white paper to learn how this innovative solution can help optimize your mAb production processes. The findings demonstrate the system's robust capability to sustain strong cell growth and high productivity, facilitating a smooth transition from laboratory to production scale.
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2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
 

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