Pfizer’s Dolsten to depart, AbbVie shakes up R&D leadership

Today’s Big News

Jul 12, 2024

Pfizer's obesity pill news leaves analysts wanting, biotech investors cheering


Immutep tries to regain pep as cancer subgroup data show path forward—with a long list of caveats


Chutes & Ladders—Pfizer's Mikael Dolsten steps down as AbbVie's R&D org switches leaders


Tiba wins BARDA contract to develop RNAi bird flu therapeutic


A look at Big Pharma’s top-paid CEOs

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Pfizer's obesity pill news leaves analysts wanting, biotech investors cheering

Pfizer gave a leg up to two obesity biotechs yesterday with the announcement that an extended-release formulation of oral med danuglipron will be advanced into dose optimization studies.
 

Top Stories

Immutep tries to regain pep as cancer subgroup data show path forward—with a long list of caveats

Immutep has spotted a potential niche for its LAG3 drug candidate, reporting phase 2b data in a subset of head and neck cancer patients to partly wipe away the stain left by an earlier readout. 

Chutes & Ladders—Pfizer's Mikael Dolsten steps down as AbbVie's R&D org switches leaders

After leading Pfizer’s R&D unit through the pandemic, Chief Scientific Officer Mikael Dolsten, M.D., Ph.D., is heading out.

Tiba wins BARDA contract to develop RNAi bird flu therapeutic

The Biomedical Advanced Research and Development Authority has awarded a $749,999 contract to Cambridge-based Tiba Biotech to develop new a RNAi-based therapeutic against bird flu.

A look at Big Pharma’s top-paid CEOs

In this week's episode of "The Top Line," Fierce Pharma’s Eric Sagonowsky and Fraiser Kansteiner discuss Fierce’s annual special report, “Big Pharma's 10 highest-paid CEOs.” 

Senate unanimously endorses legislation targeting pharma 'patent thickets'

The bill looks to limit the number of patents that companies can assert in litigation on individual products. It's intended to crack down on "patent thickets," which can delay and thwart generic competition.

How Chevron's demise could impact employers, purchasers and health payers

Industry leaders and legal observers are still coming to terms with the Supreme Court's landmark decision to overturn the Chevron doctrine.

Element Biosciences nets $277M ahead of new sequencer launch

Looking to be more upstart than startup, Element Biosciences aims to take on the DNA sequencing giant located right down the road in San Diego.

Fierce Pharma Asia—BMS, Eisai's ADC divorce; Takeda's US layoffs; House Speaker's BIOSECURE pledge

In the past two weeks, Bristol Myers Squibb has returned Eisai's FRα-targeted antibody-drug conjugate. In addition, Takeda telegraphed plans to lay off 220 employees in Massachusetts, while U.S. House Speaker Mike Johnson pledged a full floor vote on the BIOSECURE Act this year.
 
Fierce podcasts

Don’t miss an episode

A look at Big Pharma’s top-paid CEOs

In this week's episode of "The Top Line," Fierce Pharma’s Eric Sagonowsky and Fraiser Kansteiner discuss Fierce’s annual special report, “Big Pharma's 10 highest-paid CEOs.” 
 

Resources

Whitepaper

An Integrated End-to-End Approach to Antibody Drug Conjugate Development and Manufacturing

In this white paper, Lonza experts delve into the common challenges encountered by ADC developers. They explore new drug product capabilities in relation to cytotoxic drug development and manufacturing, therefore fully completing Lonza’s integrated ADC offering. Further, they discuss how this end-to-end approach can significantly accelerate the timeline to investigational new drug filing and beyond. Read this white paper to learn more.
Whitepaper

2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
Whitepaper

The “Best Practice Organization” & Its Importance for Success in Today’s Biopharma Industry

In a complex industry like biopharma, being a “Best Practice Organization” (BPO) is essential to success. But what is a BPO & how do you build one? This eBook provides the answers.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

Upcoming Fierce Events

9-12
Sep
Philadelphia, PA
11
Sep
Philadelphia, PA
17-19
Sep
Virtual Event
25-26
Sep
San Diego, CA
25-27
Sep
Philadelphia, PA

View all events