Bayer biotech nabs WRN inhibitor rights from Roche

Today’s Big News

Jun 4, 2025

Eli Lilly enlists Camurus to help unlock long-acting obesity market in deal worth up to $870M


Vigil's rare brain disease drug flunks phase 2 study, but Sanofi takeover is unaffected


Bayer's Vividion secures rights to world's only clinical-stage WRN inhibitor from partner Roche


BioAge inks option agreement for Chinese biotech's obesity asset on heels of earlier APJ agonist setback


Ascletis scores phase 3 win for daily acne pill, prepares push to Chinese regulators


Plexium cuts staff, realigns resources to support protein degrader pipeline


Fired federal workers say HHS, DOGE violated federal privacy law, mishandled personnel records 

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Featured

Eli Lilly enlists Camurus to help unlock long-acting obesity market in deal worth up to $870M

With the deal, Lilly can use Camurus' long-acting delivery technology on up to four of its own incretin compounds to develop injections in the cardiometabolic health space.
 

Top Stories

Vigil's rare brain disease drug flunks phase 2 study, but Sanofi takeover is unaffected

A phase 2 study of Vigil Neuroscience’s iluzanebart has missed its biomarker and efficacy endpoints, prompting the Sanofi-bound biotech to stop a long-term extension trial of the TREM2 agonist.

Bayer's Vividion secures rights to only clinical-stage covalent WRN inhibitor from partner Roche

Bayer’s Vividion Therapeutics has secured the global rights from its partner Roche to the only covalent Werner helicase inhibitor to have made it into the clinic.

Precision medicine’s next frontier: unlocking the power of biospecimens

Austin Read of Thermo Fisher Scientific discusses how combining biospecimens with real-world data is advancing diagnostics, treatment and the future of patient care.

BioAge inks option agreement for Chinese biotech's obesity asset on heels of earlier APJ agonist setback

Even after scrapping its lead obesity candidate due to liver toxicity, BioAge Labs is not shying away from the weight loss space. The Bay Area biotech has entered an option agreement with Chinese firm JiKang Therapeutics to potentially license a new apelin receptor (APJ) agonist nanobody.

Forging the future of cell therapy: Bayer and BlueRock’s unique journey

Discover how Bayer and BlueRock are redefining biotech partnerships. From breakthrough Parkinson’s therapies to a unique “arm’s-length” model, this episode of The Top Line dives into what makes their collaboration a blueprint for the future.

Ascletis scores phase 3 win for daily acne pill, prepares push to Chinese regulators

Ascletis Pharma’s acne pill has scored a phase 3 win, leading the Chinese biotech to claim the Sagimet Biosciences drug can hold its own against FDA-approved products Seysara and doxycycline.

Delivering the Future of Radiopharmaceuticals with Precision

Radiopharma is revolutionizing modern medicine. Discover how precision logistics empowers faster, safer delivery of life-impacting therapies when every second counts.

Plexium cuts staff, realigns resources to support protein degrader pipeline

Protein degradation company Plexium has laid off staff as part of a realignment to support the company’s pipeline, which is mostly preclinical, Fierce Biotech has learned.

Fired federal workers say HHS, DOGE violated federal privacy law, mishandled personnel records

A new class-action lawsuit asserts the Department of Health and Human Services and the Department of Government Efficiency fired civil servants based on incorrect internal personnel records.

Want to attract Gen Z talent to life sci? Try short-form social media videos, ABPI report suggests

Pharmas looking to recruit younger workers should meet Gen Z where they’re at: namely, TikTok and Instagram, according to a new report from the Association of the British Pharmaceutical Industry.

Politico: CMS' Medicaid director to depart the agency

The Trump administration's Medicaid director will depart the role as the Republicans' push to codify massive cuts to the program heats up, according to a report from Politico.

CMS rescinds guidance, letter on hospitals' obligation to provide emergency abortions

The CMS under President Joe Biden had told hospitals that life-saving abortions fall within the requirements of the federal Emergency Medical Treatment and Labor Act (EMTALA), which preempts state law.
 
Fierce podcasts

Don’t miss an episode

What’s next for tech-enabled home care? A look at the policy road ahead

This week on "Podnosis," we’re examining the future of tech-enabled home care and the policy decisions that could determine whether these models become permanent fixtures in the U.S. healthcare system.
 

Resources

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Building Peak Performance Go-to-Market Operations

We analyzed ~300 launches to identify the factors most correlated with commercial success & built a framework for peak go-to-market performance.
 

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