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May 21, 2019

Today's Rundown

Featured Story

Merck boosts late-phase cancer pipeline with $1.1B Peloton buy

Merck has struck a deal to buy Peloton Therapeutics for $1.1 billion upfront days before the biotech was due to list on Nasdaq. The deal will give Merck control of an experimental oral HIF-2α inhibitor that could challenge Keytruda for the metastatic renal cell carcinoma market.

Top Stories

Novartis, Otsuka, Pfizer, Sanofi join Verily's Project Baseline

Novartis, Otsuka, Pfizer and Sanofi have signed onto Verily’s Project Baseline, a program aimed at mapping out a baseline for human health.

Special Report—The top 11 medtech approvals of 2018

The once-straightforward definition of a medical device has begun to stretch. And for that matter, so has the definition of a medical devices company. But 2018’s top FDA green lights made one thing clear: The devices most likely to change a patient's life were designed to change their routines the least.

Ocular's sustained-release insert misses bull's-eye in phase 3 glaucoma trial

Ocular Therapeutix’s drug-eluting insert to treat glaucoma—a small, resorbable hydrogel plug that sits within the tear duct and is designed to replace 90 days’ worth of daily eye drops—fell just short of meeting the primary endpoint of its first pivotal phase 3 trial.

K2HV secures $400M to offer life science debt financing 

K2 HealthVentures has secured $400 million to support public and private companies in life sciences and healthcare. The East Coast investor will primarily provide debt financing to enable companies to reach milestones with minimal equity dilution.

Mount Sinai researchers isolate placental cells that regenerate damaged hearts in mice

Researchers at the Icahn School of Medicine at Mount Sinai have shown in a study that Cdx2 cells from the placenta can migrate through the circulatory system and target heart injuries. In male mouse models of heart attack, the cells regenerated damaged tissue.

Evotec to acquire Gates Foundation-backed Just Biotherapeutics

Biotech-CRO hybrid Evotec is continuing its deals, buys and collabs strategy with its acquisition of U.S. biologics company Just Biotherapeutics.

Resources

[Executive Summary] Achieving a Successful Drug Product Tech Transfer

Download the executive summary to learn key considerations for a successful technology transfer for manufacturing drug products, including a case study on overcoming challenges in a process transfer for a sterile diluent.

[Whitepaper] Choosing the Best Sterile Dosage Form for Phase I Clinical Supply Needs

Choosing the Best Sterile Dosage Form for Your Phase I Clinical Supply Needs.

[Whitepaper] Delivering oral solid dose product to Phase I Clinic in 14 weeks

Designed with speed & flexibility,Quick to Clinic™ for Oral Solid Dose helps deliver products to Phase I Clinic in as little as 14 weeks.

[Whitepaper] Agile Competitive Intelligence: A 3-Step Mobile Research Strategy

What is agile competitive intelligence, and how can help healthcare researchers stay ahead of the curve?

[Paid Marketplace] Accelerating DoD’s Fielding of Prototypes for Medical Countermeasures

MCS is currently seeking broad-based industry/academia collaboration on research and prototype work in technical areas related to developing medical countermeasures for the Joint Warfighter.

[Whitepaper] Now Companies Can Move Validated, Mission Critical Apps To The Cloud

Learn how the cloud can support the performance and security requirements for validated, mission-critical applications historically designed and implemented exclusively via on-premises deployment.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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