Today's Rundown Featured Story | | | Wednesday, April 29, 2020 After dribs and drabs surfacing about Gilead’s COVID-19 hopeful, remdesivir, the first data from a placebo-controlled study are here—at least, an early look at them. Remdesivir cut recovery time for hospitalized COVID-19 patients by four days, or 31%, in an NIH-sponsored study pitting the drug against placebo in more than 1,000 patients. |
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Top Stories Thursday, April 30, 2020 The first look at a much-anticipated study of Gilead’s remdesivir came not in a news release or a scientific journal, but in a White House briefing. The unorthodox data reveal was an effort to get ahead of leaks of fragmented information that could cause confusion, Anthony Fauci, M.D., director of the NIH body that sponsored the study, told Reuters. Thursday, April 30, 2020 GlaxoSmithKline is following suit with fellow British Big Pharma AstraZeneca in downplaying the overall risk to its trials during the pandemic. Monday, April 27, 2020 The life sciences industry is moving in record time to beat COVID-19, but it must connect with partners across the entire ecosystem to ramp up capabilities and deliver the billions of vaccines doses and treatments needed. Thursday, April 30, 2020 Adicet Bio has struck a deal to merge with resTORbio, bagging itself a Nasdaq listing to support its pipeline of allogeneic gamma delta CAR-T cell therapies. The combined company will take Adicet’s name and focus on its pipeline but will be led by resTORbio CEO Chen Schor. Thursday, April 30, 2020 European cancer vaccine biotech Targovax has hired a former Roche and Molecular Partners exec as its new chief scientific officer. Wednesday, April 29, 2020 Mojo Vision has raised an additional $51 million for its smart contact lens project—including the development of a tiny augmented reality display that would sit just above the pupil which could help people with impaired vision better navigate their surroundings. Thursday, April 30, 2020 Harvard scientists packed interferon gamma into little "backpacks" that can latch onto immune cells called macrophages and coax them into an anti-tumor state. Wednesday, April 29, 2020 Biopharma players worldwide have committed big money and talent to the hunt for a COVID-19 vaccine, and experts predict a shot might be available in 12 to 18 months. Behind the scenes, the Trump administration is working up a Manhattan Project-type initiative to further accelerate the work, Bloomberg reports. Resources Sponsored by: Lonza This whitepaper summarises approaches for modulating antibody effector functions and pharmacokinetics, and provides examples of antibodies in clinical studies. Sponsored by: Blue Latitude Health Report: Think you’re patient-centric? Think again. Find out how patients really feel about patient-centricity. Learn what they would like to experience along with tools and tips for maximising patient engagement across the product life cycle¬ – from clinical trials to service design and creative campaigns. Sponsored by: BBK Worldwide Leverage strategic solutions to respond to immediate challenges to patient and site engagement from COVID-19, and learn to maximize the FDA guidance on the conduct of clinical trials during a pandemic. 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Sponsored by: Applied BioMath Learn how we used a tiered model-based approach of a bispecific antibody to appropriately cover multiple antigen pairs to help teams with informed antibody design, prioritization of experiments, and triaging of challenging antigen pairs Sponsored by: Altran This whitepaper highlights the challenges of implementing the right digital twin strategy while providing key use cases in the manufacturing domain for which a digital twin is extremely useful and several examples of technology trends that will shape the future. Sponsored by: Outer Edge Technology To survive in these challenging conditions, companies need to promptly address business continuity issues - especially the remote delivery of data and voice solutions. See how Outer Edge can help. Sponsored by: Patheon, by Thermo Fisher Scientific Poorly soluble molecules hindering your workflow? Sponsored by: eClinical Solutions Key findings from the 2019 Life Sciences Data & Analytics Survey conducted by the Tufts Center for the Study of Drug Development will be unveiled during this live webinar led by industry expert and study lead, Ken Getz, Director of Sponsored Programs and Associate Professor. Sponsored by: Catalent Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study. Sponsored by: Catalent Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study. Sponsored by: Catalent Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study. Sponsored by: Catalent This whitepaper discusses the benefits of end-to-end solutions and share case studies on how flexible manufacturing strategies can accommodate the changing landscape of pharmaceutical products and help bring a drug to market. Sponsored by: Catalent Get expert insights on strategies to implement flexible manufacturing and different technologies that are easily scalable and reproducible. Sponsored by: Catalent Regardless of the assigned FDA expedited approval designation and approach, the key action items should be: the assurance of a detail-oriented plan and the adaption of a “forward-thinking” approach that will assist in any future challenges and opportunities for growth of each project. Sponsored by: Clarify Health Pharma launch teams spend significant resources on data and analytics with limited ROI. Read this case study to learn how a Life Sciences company identified two times more patients best suited for therapy, using Clarify’s deep and longitudinal patient and HCP insights. | 
