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April 25, 2017

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Today's Rundown

  1. Novartis confirms that Juliet CAR-T data out in June

  2. With a sense of inevitability, OncoMed swings the ax on half of staffers

  3. Ex-Kythera team raises $40M for dermatology clinical trials

  4. [Sponsored] Mitotech’s SkQ1 targets mtROS, and a long list of age-related diseases

  5. Circassia defends allergy flops as business reboot continues

  6. Is Amgen losing confidence in Novartis-partnered migraine program?

  7. Two Pore Guys raises $24M+ for handheld nanopore diagnostic tool

  8. Sanofi, Amgen and Google-backed Science 37 raises $29M in Series C

  9. Biogen's Spinraza scores later-onset SMA data for stepped-up push with payers

Featured Story

Novartis confirms that Juliet CAR-T data out in June

Novartis HQAfter Jefferies analyst Biren Amin said last night that he thought Novartis would be presenting its midstage CAR-T blood cancer data from Juliet at a Swiss conference in mid-June, the Big Pharma has confirmed to FierceBiotech that it will indeed be posting the long-awaited data. 

Top Stories

With a sense of inevitability, OncoMed swings the ax on half of staffers

It’s been a torrid few weeks for pressured OncoMed with trial woes compounded by partners walking away. Now, after hinting at cuts earlier this month, the biotech will shed 50% of its workforce. 

Ex-Kythera team raises $40M for dermatology clinical trials

Sienna Biopharmaceuticals has raised $40 million to advance its pipeline of clinical-phase aesthetic and dermatology assets. The Series B round continues the rapid rise of Sienna, which has raised $74 million and bought Creabilis since it emerged helmed by the ex-Kythera Biopharmaceuticals team last year. 

[Sponsored] Mitotech’s SkQ1 targets mtROS, and a long list of age-related diseases

It’s a critical tradeoff for life. Our bodies use sugar and fat from the food we consume to produce energy in our cells’ mitochondria, the internal powerhouses that give us the energy we need for all our vital functions.

Circassia defends allergy flops as business reboot continues

Circassia CEO Steve Harris has defended the running of the company’s allergy trials, stating nothing could have been done better. Harris made the comments after presenting annual results that mark another step in the transition of Circassia away from its original area of focus.

Is Amgen losing confidence in Novartis-partnered migraine program?

Novartis will play a bigger role in the marketing of migraine drug erenumab—thanks to a reworking of its 2015 commercialization deal with Amgen—but analysts say the move may reflect reduced sales expectations.

Two Pore Guys raises $24M+ for handheld nanopore diagnostic tool

Two Pore Guys closed a $24.5 million Series A round, which will boost the manufacturing of the company’s handheld testing system, as well as further develop its nanopore technology for whole genome sequencing and genome mapping.

Sanofi, Amgen and Google-backed Science 37 raises $29M in Series C

After raising $31 million just last year, California-based clinical research company Science 37 has now served up a Series C round worth $29 million. Glynn Capital Management led the cash boost with help from Google’s venture firm GV, as Science 37 plots scaling up its operations and expanding around the globe.

Biogen's Spinraza scores later-onset SMA data for stepped-up push with payers

Hoping to win over careful payers, Biogen has new data to support its superpricey spinal muscular atrophy (SMA) drug Spinraza.

News of Note

Bispecific-focused China biotech EpimAb Biotherapeutics has raised $25 million in its Series A funding round. Statement

Neurodegenerative disease and RNA biotech Aquinnah Pharmaceuticals has been given a $10 million investment boost from Pfizer and AbbVie. Release

DelMar Pharmaceuticals has penned a new, three-year collaboration with Duke University for VAL-083 in an aggressive form of brain cancer. Statement

Resources

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[Whitepaper] DocuSign Life Sciences eBook: Reducing Cycle Time with Digital Transaction Management

The patients who rely on your scientific leadership are expecting more.

[Whitepaper] Streamline Regulatory Compliance in Life Sciences with Digital Transaction Management

The U.S. Department of Justice has collected upwards of $17 billion in settlements from the healthcare industry since 2009, including more than $2 billion from a single life sciences company.

Events

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