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April 18, 2017

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Today's Rundown

  1. Novartis gets second CAR-T candidate FDA ‘breakthrough’ tag

  2. Allergan injects Tobira candidate into Novartis NASH combo trial

  3. Circassia scraps allergy program after another trial flops

  4. Motif Bio antibiotic hits endpoint in skin infection phase 3

  5. Ionis looks east, teaming up with Ribo to bring RNA drugs to China

  6. Bristol-Myers, Nordic Bioscience team up on NASH biomarkers

  7. Celgene in Asia-Pacific collab with Antengene, Tigermed as clinical support

  8. Cobra Biologics to pump $19M into its U.K. and Swedish production facilities

Featured Story

Novartis gets second CAR-T candidate FDA ‘breakthrough’ tag

As the battle between Swiss major Novartis and biotech rival Kite Pharma heats up to be the first to market a CAR-T cancer med, the Big Pharma has been handed its second FDA "breakthrough" tag for its eagerly awaited JULIET trial.

Top Stories

Allergan injects Tobira candidate into Novartis NASH combo trial

Allergan has wasted little time in testing out its new fatty liver candidate that it got in the potentially $1.7 billion buyout of Tobira last year as it pens a new deal to wed cenicriviroc to Novartis’ lead FXR agonist in a midstage test.

Circassia scraps allergy program after another trial flops

Circassia has pulled the plug on its allergy programs after falling short in another study. The string of failures continued with the publication of subpar data from a house dust mite allergy phase 2b, forcing the company to pivot away from the assets that drove it to a £200 million ($251 million) IPO in 2014.

Motif Bio antibiotic hits endpoint in skin infection phase 3

Motif Bio has posted data from a phase 3 trial of its antibiotic candidate iclaprim. The drug held its own against established antibiotic vancomycin, setting Motif Bio on a path it sees leading to a filing for FDA approval in the first half of next year.

Ionis looks east, teaming up with Ribo to bring RNA drugs to China

Ionis Pharmaceuticals has enlisted the help of Suzhou Ribo Life Science to help it bring three of its RNA-based drugs to the Chinese market.

Bristol-Myers, Nordic Bioscience team up on NASH biomarkers

Bristol-Myers Squibb and Denmark’s Nordic Bioscience inked a deal to develop biomarker technology to diagnose and monitor fibrotic diseases such as nonalcoholic steatohepatitis (NASH).

Celgene in Asia-Pacific collab with Antengene, Tigermed as clinical support

Celgene has reached its first licensing agreement in the Asia-Pacific region with China-based young biotech Antengene, which will be helped by CRO Tigermed with clinical development.

Cobra Biologics to pump $19M into its U.K. and Swedish production facilities

Cobra Biologics will inject $19 million into facilities located in the U.K. and Sweden to help the CDMO meet increased demand from gene and immunotherapy companies, the company said.

News of Note

Cancer biotech and biopharma favorite Zymeworks has set terms for its $65 million initial public offering. Renaissance Capital article

Belgium-based inflammatory biotech Galapagos saw its public offering total $338 million. Statement (PDF)

Struggling CAR-T biotech Juno Therapeutics has taken on former Genentech exec Sunil Agarwal as president of its research and development unit. Release

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