Roche touts near-complete MS suppression with Ocrevus

Today’s Big News

Apr 17, 2024

Pfizer's academic-partnered R&D unit is scrapped as part of cost-cutting measures


Eli Lilly’s edge over GLP-1 rivals tipped to drive Mounjaro sales to $34B by 2029


Roche touts near-complete suppression of multiple sclerosis relapse for injectable Ocrevus


Abbott’s gains in medical device sales push quarterly haul to nearly $10B


Sage burns Parkinson’s bridge, flunking first of 4 midphase tests for key prospect


Eli Lilly's tirzepatide scores again, this time in 2 sleep apnea trials

 

Featured

Pfizer's academic-partnered R&D unit is scrapped as part of cost-cutting measures

Pfizer's 2023 cost-cutting wave swept up a specific R&D team that worked closely with academics to swiftly develop new medicines. A company spokesperson confirmed that Pfizer has closed labs associated with the Centers for Therapeutic Innovation.
 

Top Stories

Eli Lilly’s edge over GLP-1 rivals tipped to drive Mounjaro sales to $34B by 2029

GlobalData has put out a forecast that shows how GLP-1 drugs could rapidly redefine what big looks like in drug sales. The analysts expect Mounjaro to bring in as much in 2029 as Eli Lilly’s entire portfolio did in 2023—and are tipping its Alzheimer’s disease prospect donanemab to add a further $5 billion.

Roche touts near-complete suppression of multiple sclerosis relapse for injectable Ocrevus

One-year data continued to support a more convenient, injectable version of Roche’s blockbuster multiple sclerosis drug Ocrevus ahead of an FDA decision, the Swiss pharma said.

Abbott’s gains in medical device sales push quarterly haul to nearly $10B

Abbott’s medical device division’s sales grew by 14.2%, powered by double-digit growth across electrophysiology, neuromodulation and structural heart.

Sage burns Parkinson's bridge, flunking first of 4 midphase tests for key prospect

Sage Therapeutics has set a bad PRECEDENT for dalzanemdor. The therapy failed to improve cognitive ability in a phase 2 Parkinson’s disease study, setting Sage off on the wrong foot at the start of a sequence of readouts that will define the future of the molecule.

Eli Lilly's tirzepatide scores again, this time in 2 sleep apnea trials

In addition to their acclaimed efficacy against diabetes and obesity, GLP-1 drugs are gaining traction for their potential to treat a variety of other common disorders. Now, two trials have shown that Eli Lilly’s weight loss product Zepbound (tirzepatide) can help patients overcome obstructive sleep apnea (OSA).

Arrowhead's plozasiran could reach $700M-plus in sales by 2032, meet major unmet need in dyslipidemia: GlobalData

The drug has shown promise in reducing triglycerides and the protein APOC3, meaning it could be used to treat many forms of dyslipidemia, a family of diseases in which lipids or lipoproteins are found in abnormally high or low amounts in the blood.

Boosted by $19M equity package, Teva's Richard Francis joins upper echelons of pharma CEO pay ranks

Riding high on Teva’s success under its recent “Pivot to Growth” strategy, chief executive Richard Francis—in his first year at the helm of the generics and innovative medicines hybrid—has emerged as one of the industry’s top-paid CEOs for 2023.

Lilly Alzheimer's med glides out of Leqembi's slipstream with FDA adcomm request

Fervent FDA watchers may note that the FDA typically warms to subsequent drugs in a class as they come in for review. But the Alzheimer’s space has never been like any other therapeutic area, so why would the regulatory process be any different?

Sanofi shrinks IGM antibody partnership amid pipeline reprioritization

Sanofi’s global collaboration with IGM Biosciences has shrunk by half. The companies will now focus only on developing three IgM agonist antibodies for immunology and inflammation and shed three related oncology targets.

FDA delivers de novo clearance to Scopio’s bone marrow pathology AI for blood disorders, cancer

The company’s all-digital cell morphology analysis platform employs high-resolution microscopic imaging of samples taken during bone marrow aspiration procedures and automatically highlights different hematopoietic cell types in stained blood smears.

Pfizer’s latest ‘Dear Scientist’ video stars a long COVID patient looking for answers

As COVID-19 moves into an endemic phase, though rates of coronavirus infections and hospitalizations continue to fall, cases of long COVID appear to be slowly ticking upward.

CDMO Fujifilm Diosynth's restructuring plan may leave up to 240 staffers out of work

The CDMO is reworking its small-scale business unit, which includes four global facilities, after a lack of investment in early-stage cell and gene therapy research projects.
 
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Industry Events

Drug Development Boot Camp® VIRTUAL | Spring 2024

April ‌10-11, ‌2024

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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