New approach shows promise in pediatric cancers

Today’s Big News

Apr 11, 2024

Regeneron hit with DOJ complaint that it hid 'hundreds of millions' in Eylea credit card processing fees from Medicare 


For Chinese biotechs, the out-licensing business is scorching hot. Could geopolitics rain on their parade? 


Precision medicine approach combining AI, DNA and drug testing shows gains against relapsed childhood cancers 


Vertex pays $4.9 billion to hike Alpine’s immunology trail 


Number of ongoing US drug shortages reaches new high, pharmacist group says 


Fierce Biotech Layoff Tracker 2024: Genentech, Novartis and Sanofi lay off staff 


Fujifilm Diosynth blueprints another $1.2B expansion at NC plant where it aims to employ 1,400 

 

Featured

Regeneron hit with DOJ complaint that it hid 'hundreds of millions' in Eylea credit card processing fees from Medicare

The U.S. government is accusing Regeneron of deliberately using an unusual method to overcharge Medicare for the company’s popular eye drug Eylea.
 

Top Stories

For Chinese biotechs, the out-licensing business is scorching hot. Could geopolitics rain on their parade?

Chinese biotechs have never had so much success inking cross-region out-licensing deals. But could an increase in national security dampen the scorching-hot space?

Precision medicine approach combining AI, DNA and drug testing shows gains against relapsed childhood cancers

The process, being developed by First Ascent Biomedical, showed promise in a small study published this week in Nature Medicine.

Vertex pays $4.9 billion to hike Alpine’s immunology trail

Vertex is buying Alpine Immune Sciences for $4.9 billion, the companies announced Wednesday. At the center of the deal is Alpine's midstage IgA nephropathy treatment.

Number of ongoing US drug shortages reaches new high, pharmacist group says

The American Society of Health-System Pharmacists has released new data showing there were 323 drugs in shortage in the U.S. as of 2024’s first quarter—the highest number recorded since ASHP began tracking shortage data back in 2001.

Fierce Biotech Layoff Tracker 2024: Genentech, Novartis and Sanofi lay off staff

We really didn't want to have to create another Layoff Tracker this year. But here we are, launching the third annual iteration tracking biopharma layoffs. 

Fujifilm Diosynth blueprints another $1.2B expansion at North Carolina plant where it aims to employ 1,400

Fujifilm Diosynth is investing $1.2 billion more to soup up its end-to-end biomanufacturing facility in Holly Springs, North Carolina, bringing the total project to more than $3.2 billion, the company said Thursday. The latest expansion is expected to create 680 new jobs.

Peak Rock Capital takes a bite out of Steris with $787M dental business deal

Collectively known as the HuFriedyGroup, the 1,500-employee international division manufactures dental instruments, infection prevention products and patient sedation systems, including the long-time brands of Hu-Friedy, Crosstex, Omnia and Accutron.

Novartis pays $150M for Arvinas' phase 3-ready prostate cancer protein degrader

Novartis is adding another weapon to its arsenal of oncology therapies, paying Arvinas $150 million upfront for rights to a phase 3-ready protein degrader that could treat a wide range of prostate cancer patients.

Castle Biosciences fortifies support of Esophageal Cancer Awareness Month with fundraising, educational collabs

Castle Biosciences is giving Esophageal Cancer Awareness Month the royal treatment, spending April sponsoring a series of events and initiatives to improve education, prevention and research around the condition.

Alzheimer's blood test from Roche, Eli Lilly nabs FDA breakthrough tag

After more than a year in the works, Roche and Eli Lilly have taken a step closer to delivering their blood test to help diagnose Alzheimer’s disease.

Facing uncertain vaccine demand, Moderna halts mRNA plant buildout in Kenya

The company's planned site is now on the back burner after a lack of vaccine demand from Africa and cancelled orders have stacked up to more than $1 billion in losses, Moderna said in a statement.

Nearly a week after pulling Relyvrio, Amylyx to engage regulators about the drug's path in another rare disease

On the heels of Relyvrio’s market withdrawal in amyotrophic lateral sclerosis, Amylyx Pharmaceuticals has shared early data from a phase 2 trial in a separate rare disease that the biotech is touting as “clinically meaningful.”
 
Fierce podcasts

Don’t miss an episode

The unrecognized threat of PAD

This week on “The Top Line,” join Editor-in-Chief of Fierce Life Sciences and Healthcare Ayla Ellison as she sits down with Kumar Madassery, M.D., Director of Peripheral Vascular Intervention & CLI Program at Rush University Medical Center, to explore peripheral arterial disease—a serious health issue that is often overlooked and undermanaged.
 

Resources

eBook

Discover the future of mAb manufacturing

Unlock the future of mAb manufacturing with our complete guide to integrating the revolutionary Gibco™ Efficient-Pro™ Medium and Feeds System, enhancing productivity and quality for exceptional outcomes 
Whitepaper

Oncology Market Outlook 2024

This paper assesses the current state of the oncology market, reviewing key expectations for 2024. It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation.
Whitepaper

Guidance for Biotechs Choosing Next-Gen Contract GMP/CMC Labs

Choosing the right contract lab can help drug developers accelerate their timelines and generate cost-efficiencies. For insights into what to look for when selecting a GMP/CMC lab partner read this white paper which delves into a range of factors that can support your needs in both the short-term and in planning for the future.
 

Industry Events

Drug Development Boot Camp® VIRTUAL | Spring 2024

April ‌10-11, ‌2024

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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