Xi Jinping hosts pharma CEOs in China

Today’s Big News

Mar 28, 2025

Novartis’ prostate cancer drug Pluvicto wins key FDA nod toward $5B-plus sales target 


Novo inks $1B biobucks Lexicon obesity deal after seeing preclinical prospect shine with semaglutide 


AstraZeneca, Sanofi, Lilly, Pfizer CEOs meet with Xi Jinping amid US-China trade tensions


Abbott secures European approval for Volt pulsed field ablation system 


Moderna brand chief Kate Cronin leaves for 'next chapter' 


‘It’s just ugly’: Federal funding cuts to Columbia University leave chronic fatigue research in limbo 


Sanofi's versatile Qfitlia scores FDA nod to enter crowded hemophilia market 

 

Featured

Novartis' prostate cancer drug Pluvicto wins key FDA nod toward $5B-plus sales target

After much delay, Novartis has finally won a key FDA go-ahead for Pluvicto, opening up the radioligand therapy to a much broader prostate cancer population.
 

Top Stories

Novo inks $1B biobucks Lexicon obesity deal after seeing preclinical prospect shine with semaglutide

Lexicon Pharmaceuticals’ pursuit of the last word in obesity candidates has attracted Novo Nordisk. The Danish drugmaker is betting $75 million in upfront and near-term milestone payments to secure global rights to a preclinical prospect that paired well with its GLP-1 blockbuster semaglutide in mice.

AstraZeneca, Sanofi, Lilly, Pfizer CEOs meet with Xi Jinping amid US-China trade tensions

As U.S. President Donald Trump threatens a new round of tariffs as part of an onshoring push, Chinese President Xi Jinping is courting foreign investment as well, including from drugmakers.

Abbott secures European approval for Volt pulsed field ablation system

Abbott is joining the worldwide race to make pulsed field ablation the standard procedure for atrial fibrillation.

Moderna brand chief Kate Cronin leaves for 'next chapter'

Kate Cronin, who took the marketing reins at Moderna in 2021 as it was skyrocketing to global renown for its COVID-19 vaccine, is stepping down from her post.

'It's just ugly': Federal funding cuts to Columbia University leave chronic fatigue research in limbo

Earlier this month, Ian Lipkin, M.D., and his team at Columbia University submitted a paper for publication that suggests certain approved drugs could possibly be repurposed for a severe fatigue condition that currently has no approved treatment, while also highlighting prospective targets for new therapeutics. A week later, the NIH terminated grant funding to Columbia's center studying the condition.

Sanofi's versatile Qfitlia scores FDA nod to enter crowded hemophilia market

Over the last three years, the FDA has approved six new drugs for hemophilia. And now the U.S. regulator has signed off on another, Sanofi’s Qfitlia, which sets itself apart as the only treatment for all types of hemophilia.

Another big payday for O'Day as Gilead boosts his compensation 5% to $23.7M

Gilead CEO Daniel O’Day saw another rise in his pay in 2024, reflecting the steadily upward trajectory of the company since he took the reins in 2019. O’Day received a compensation package of $23.7 million last year, a 5% boost on his $22.6 million pay from 2023.

Chutes & Ladders—Yet another exec departs CRISPR Tx

CRISPR Therapeutics’ Julianne Bruno is hitting the exit in favor of external opportunities, marking the latest shakeup to the company’s executive team. Bruno had been with CRISPR for six years, serving in several management roles with increasing responsibility before landing the chief operating officer position last May.

BioNTech shows off lung cancer survival data behind phase 3 push for red-hot bispecific

BioNTech has shown why it made small cell lung cancer a priority for its PD-L1xVEGF-A bispecific. The biotech linked BNT327 to a median overall survival of 16.8 months in a Chinese phase 2 trial, suggesting the drug candidate could set a new benchmark in a market served by AstraZeneca and Roche.

Visby Medical nets FDA clearance for completely at-home STI test

Visby's kit includes vaginal self-collection swabs and a palm-sized, PCR-based testing device for chlamydia, gonorrhea and trichomoniasis, which delivers a result within 30 minutes.

Eli Lilly's Alzheimer's contender Kisunla gets thumbs down from EU regulators over safety concerns

After failing to pass muster with England’s drug reimbursement watchdog earlier this month, Eli Lilly’s Alzheimer’s disease med Kisunla also got a rejection from EU regulators.

BioAtla lays off 30% of staff, hunts out partners for ADC and cancer antibody

BioAtla is laying off 30% of staff as the biotech searches for partners for some of its conditionally active biologic antibodies while eking out its cash to cover a slew of clinical readouts over the next couple of years.

Ionis, Arrowhead, Amarin sponsor new triglyceride group to educate physicians

Ionis Pharmaceuticals and Arrowhead Pharmaceuticals have found a common cause amid their emerging rivalry. With the pair preparing to go head to head in a rare disease market, the companies signed up to be the top two sponsors of the newly launched National Triglyceride Alliance.
 
Fierce podcasts

Don’t miss an episode

What diversity means in medtech

This week on "The Top Line," we hear from Nada Hanafi, co-founder of MedTech Color, about the importance of diversity in healthcare settings.
 

Resources

Whitepaper

The Oncology Market: 2025 Outlook

Read about four trends that will shape the innovations, therapies, & market landscape in oncology during 2025 & beyond.
Whitepaper

Redefining vaccine trial recruitment

Discover how to revolutionize your vaccine trials with Avacare's latest white paper. Gain exclusive access to innovative, data-driven recruitment strategies that ensure diverse, efficient, and high-quality vaccine trials.
Whitepaper

Solutions for CAR-Engineered Cell Characterization

Develop your CAR molecule faster
 

Upcoming Fierce Events

3-10
Mar-Apr
Accepting Nominations Now
3-10
Mar-Apr
Accepting Nominations Now
29-1
Apr-May
San Diego, CA
7-9
May
Free Virtual Event
14
May
Free Virtual Event

View all events