This week's sponsor is CMIC Group. | | Considering Japanese Market Entry? As Japan's largest CRO with end-to-end solution, CMIC Group is your most experienced partner in Japan & the US. Our experts will help you determine the best strategy at any stage of drug development. Click here to learn more! | Today's Rundown Aerpio shares plummet on eye study flop Allergy Therapeutics’ shares nose-dive as another setback hits the biotech Dermira soars as Dupixent challenger hits midphase endpoint Cold Genesys bags $22M to push oncolytic virus for bladder cancer After a hiring blitz, Karuna nabs $68M funding round Imara lands $63M crossover round to trial sickle cell drug Apple presents smartwatch results from 400,000-strong heart study Featured Story | Monday, March 18, 2019 Shares in Aerpio Pharmaceuticals were more than halved in early trading Monday morning after the company announced the failure of its leading drug candidate. |
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| Top Stories Monday, March 18, 2019 Allergy Therapeutics saw its stock down by 40% in early trading in London Monday morning after its birch pollen drug failed to move the needle in a key phase 3 trial, though the biotech, no stranger to setbacks, has vowed to keep calm and carry on. Monday, March 18, 2019 Dermira has generated evidence that its treatment for moderate-to-severe atopic dermatitis can pose a challenge to Dupixent. The phase 2b data link the treatment to significant gains on an eczema scale but leave doubts about whether it can improve on the dosing of Regeneron and Sanofi’s fast-selling drug. Monday, March 18, 2019 Cold Genesys is developing its lead asset both as a single agent and in combination therapies and has taken it through phase 2 in nonmuscle invasive bladder cancer. Monday, March 18, 2019 Boston startup Karuna Therapeutics has raised a chunky $68 million just six months after getting off a $42 million series A as it looks to beef up work on its Alzheimer’s/schizophrenia combo therapy. Monday, March 18, 2019 Imara has raised a $63 million crossover round to advance its sickle cell disease drug. The series B will enable Imara to wrap up a phase 2a trial of a phosphodiesterase-9 inhibitor it picked up from Lundbeck and push deeper into the clinic. Monday, March 18, 2019 After canvassing more than 400,000 people across all 50 states in just eight months, Apple has finished a virtual investigation of its smartwatch’s ability to alert users to irregular heart rhythms possibly linked to atrial fibrillation. It was one of the largest studies of its kind. This week's sponsor is Accenture. | | [Webinar] Embracing Emerging Technology in Drug Development Wednesday, March 27 | 10am ET / 7am PT During this webinar, attendees will learn how organizations can rapidly adopt digital solutions while maintaining a focus on the patient, harmonize a rapidly transforming workforce with new technological capabilities, and align new technologies with an organization's R&D strategy and goals for profitable growth. Register Now! | Resources Sponsored by: InterSystems Analytics using patients’ real-time longitudinal laboratory results, and claims data, yielded higher value information and new revenue streams for TriCore reference laboratories. Sponsored by: InterSystems Whitepaper on leveraging normalized real-world patient data to streamline clinical trials, reduce delays and lower costs. Sponsored by: Outer Edge Technology Software end of life puts you at risk for data breaches, business disruption and liability. Sponsored by: Patheon, part of Thermo Fisher Scientific The Right Partner Can Improve Flexibility and Mitigate Risks from Forecast Inaccuracy in Biomanufacturing. Sponsored by: Patheon, part of Thermo Fisher Scientific Download this whitepaper to learn more. Sponsored by: ON24 Which HCP Touchpoints and channels are yielding the best results in today’s digital world? Sponsored by: Blue Matter White paper outlining the key types of cell-based immunotherapies in oncology, as well as the development and commercial outlook for each. Sponsored by: AlphaSense It’s never been more challenging to stay on top of trends and innovation shaping the future of healthcare. Discover how AI can help competitive intelligence teams achieve more proactive strategies. Sponsored by: Biotech Primer The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry. BioBasics: Biotech For The Non-Scientist March 28-29, 2019 | Boston, MA Drug Development Immersion April 3-4, 2019 | Philadelphia, PA BioBasics: Biotech For The Non-Scientist May 8-9, 2019 | New York, NY Drug Development Immersion May 16-17, 2019 | Boston, MA 2019 BIO International Convention June 3-6, 2019 | Philadelphia, PA FierceBiotech Executive Breakfast at BIO 2019 – Getting Real: The Changing Tide on Real-World Evidence in Drug Development June 5, 2019 | Philadelphia, PA Drug Development Boot Camp® 2019 November 20-21, 2019 | Boston, MA | Register and start preparing Today! Calling Europe – Drug Development Boot Camp® 2019 November 20-21, 2019 | Boston, MA | Register and start preparing Today! |