BMS scraps Fulcrum partnership

Today’s Big News

Mar 5, 2025

DOGE terminates leases for 30 FDA sites across 23 states


Jazz hands over $935M to buy Chimerix for near-approval cancer drug


BMS pushes Fulcrum off its list of partners, scrapping MyoKardia heart muscle pact


Former NIH director Francis Collins retires, calls the agency the 'main piston' in biomedical discovery


ALX lays off 30% of staff to pay for more trials of CD47 blocker


Celon's PDE10A inhibitor reduces involuntary movements in midstage Parkinson's trial


BioNTech’s phase 1/2 malaria vaccine trial hit by FDA hold 


NIH cancels some grants for LGBTQ+ health research effective immediately: Stat


Blackstone buys majority stake in Japan's largest contract research organization

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

DOGE terminates leases for 30 FDA sites across 23 states

Under President Donald Trump’s administration, the DOGE has reportedly terminated leases for at least 748 federal sites, including 30 FDA facilities across 23 states.
 

Top Stories

Jazz hands over $935M to buy Chimerix for near-approval cancer drug

Jazz Pharmaceuticals has drummed up a deal in double time, agreeing to buy Chimerix for $935 million just days after its CEO voiced an interest in diversifying the pipeline.

BMS pushes Fulcrum off its list of partners, scrapping MyoKardia heart muscle pact

Bristol Myers Squibb is levering Fulcrum Therapeutics out of its life. MyoKardia, a biotech BMS bought in 2020, was working with Fulcrum to find cardiomyopathy targets but recently decided to end the alliance.

Former NIH director Francis Collins retires, calls agency the 'main piston' in biomedical discovery

After a 32-year career at the National Institutes of Health, Francis Collins, M.D., Ph.D., retired from the agency effective Feb. 28.

ALX lays off 30% of staff to pay for more trials of CD47 blocker

ALX Oncology is laying off 30% of its workforce as the biotech seeks to channel its cash into further trials of its CD47 blocker.

Celon's PDE10A inhibitor reduces involuntary movements in midstage Parkinson's trial

Celon Pharma’s PDE10A inhibitor has reduced involuntary movements in a phase 2 trial of individuals with Parkinson’s disease.

BioNTech's RNA malaria vaccine trial hit by FDA hold

The FDA has placed a hold on BioNTech’s phase 1/2a trial, pausing the company’s efforts to develop a RNA-based vaccine for malaria prevention.

NIH cancels some grants for LGBTQ+ health research effective immediately: Stat

Several scientists studying LGBTQ+ health issues have had their grants from the National Institutes of Health canceled effective immediately, according to a March 3 report from Stat.

Blackstone buys majority stake in CMIC, Japan's largest contract research organization

Private equity giant Blackstone is going big on Japan, acquiring a majority stake in the country’s leading contract research organization.

UPDATE: Bristol Myers' cost-savings drive claims another 280 jobs in US

Beginning in late May, BMS will lay off 223 workers in Lawrenceville, New Jersey, where the company hosts its corporate headquarters, as well as a facility for commercial and late-stage development work. Separately, the company is laying off 57 employees at a research site in California. The downsizing initiative is part of BMS’ broader effort to cut costs.

VA terminates 585 'non-mission-critical or duplicative' contracts to redirect over $900M to vet care

The VA said its cuts are the “first step” in its audit of the roughly 90,000 contracts it currently has in place—a process its announcement stressed is being conducted with in-house expertise and feedback. Specific plans for the savings will be shared "in the coming weeks and months," the department said.

IQVIA launches digital tool for ordering lab tests and managing specimens

Global contract research organization IQVIA is looking to simplify workflows for its clinical trial investigators with a new bundle of digital applications.
 
Fierce podcasts

Don’t miss an episode

What’s next for digital health investing in 2025?

Digital health venture capital funding cooled off in 2024 following the fever pitch of investment from 2020 to 2022. But investors still see bright opportunities for the sector.
 

Resources

Whitepaper

The Oncology Market: 2025 Outlook

Read about four trends that will shape the innovations, therapies, & market landscape in oncology during 2025 & beyond.
Whitepaper

Redefining vaccine trial recruitment

Discover how to revolutionize your vaccine trials with Avacare's latest white paper. Gain exclusive access to innovative, data-driven recruitment strategies that ensure diverse, efficient, and high-quality vaccine trials.
Whitepaper

Solutions for CAR-Engineered Cell Characterization

Develop your CAR molecule faster
 

Upcoming Fierce Events

29-1
Apr-May
San Diego, CA
7-9
May
Free Virtual Event
14
May
Free Virtual Event
15-15
Aug-Nov
Submissions Open Early August
8-11
Sep
Philadelphia, PA

View all events