Today's Rundown Eagle and Mystic lead AstraZeneca’s cancer clear out Liver toxicity concerns spike Motif Bio’s iclaprim filing Axovant sends off its small molecule team with an epilepsy drug and $100M in funding commitments [Sponsored] Invert to Convert: Rethinking Patient Recruitment & Enrollment Strategies 5AM, JJDC get in on $42M series A round for cell therapy player Vor Biopharma Novartis inks 10-target antibody discovery deal with AbCellera Amgen taps Abilita Bio’s membrane protein technology Featured Story | | | Thursday, February 14, 2019 AstraZeneca has cleared a clutch of cancer programs from its clinical pipeline. The PD-L1 combination trials Eagle and Mystic led the clear out, and the immuno-oncology drugs tested in those studies feature heavily in the earlier-phase cull. |
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| This week's sponsor is Camargo. | | | [Webinar] Maximizing the Value of Your Drug Development Program
Thursday, February 21 | 11am ET / 8am PT
This webinar will benefit executives at Biotech and Pharmaceutical companies interested in learning more about 505(b)(2) drug development and how to save time and money while maximizing the value of their drug development program. Register Now! |
Top Stories Thursday, February 14, 2019 Motif Bio’s hope of adding to the antibiotic armamentarium for serious bacterial infections has just been dealt a blow by the FDA. Thursday, February 14, 2019 Axovant has spun off its small molecule team into a new company, Arvelle Therapeutics, as it continues its march toward becoming a biotech with a sole focus on gene therapies. Monday, February 11, 2019 90% of clinical trials will meet their enrollment goals if their original timelines are doubled. WCG breaks down the barriers to ramping up and meeting patient enrollment goals. A new approach addresses root causes and accelerates study timelines by 33%. Thursday, February 14, 2019 The funding will advance Vor's lead asset, an engineered hematopoietic stem cell (HSC) therapy for acute myeloid leukemia, as well as the development of a pipeline of HSC-based treatments for other blood cancers. Thursday, February 14, 2019 Novartis has struck a deal to apply AbCellera’s antibody discovery capabilities to up to 10 targets. The deal sees Novartis join GlaxoSmithKline, Merck and Pfizer on the list of companies partnered with the antibody discovery shop. Thursday, February 14, 2019 Amgen and Abilita Bio have inked a research deal in which Abilita will use its Enabled Membrane Protein platform to help Amgen work to develop drugs for challenging targets. Enrollment Showcase | | | Sponsored by: Drexel University Online Drexel University’s online graduate programs in biomedicine, clinical research, drug discovery, and molecular medicine were developed with working professionals in mind, providing you with the education, practical skills, and competitive edge you need to be successful in your career. Learn more. |
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Resources Sponsored by: AlphaSense It’s never been more challenging to stay on top of trends and innovation shaping the future of healthcare. Discover how AI can help competitive intelligence teams achieve more proactive strategies. Presented by: SDC If commonly used statistical phrases like two-sample t-test, difference in proportions, or hazard ratio intimidate you, join this webinar for an introduction to statistical analyses in clinical trials. Sponsored by: Patheon, part of Thermo Fisher Scientific When a biologics company prepares to launch a new product, it must forecast the manufacturing capacity it will need, factoring in its estimate of the size of future sales, the timing of the launch, the dosage of the product, its strategy for building its market and a host of other variables. Sponsored by: Oracle Health Sciences 92% of survey respondents make changes to their RTSM/IRT systems due to study changes. See what else puts a strain on their clinical trials. Download the Research Whitepaper. Sponsored by: Patheon, part of Thermo Fisher Scientific Download this whitepaper to learn more. Sponsored by: The Kinetix Group Explore how the pharma industry can adapt its approach to the changing healthcare marketplace in the era of the Quadruple Aim Sponsored by: Cofactor Genomics Learn how Health Expression Models provide increased sensitivity, specificity, and accuracy for characterizing immune response in solid tumor specimens. Sponsored by: BioAnalytix, Inc. This whitepaper reviews fundamental aspects of HCPs that pertain to biologic drug development and presents current and emerging approaches to HCP analysis. Sponsored by: Veradigm Clinical trials take too long and cost too much—here's what needs to change. Sponsored by: Reprints Desk, Inc. Go from Search to Full-Text Scientific Papers in a Single Click! Sponsored by: Blue Latitude Health This white paper consists of original data and expert interviews. Download it today for exclusive tools, tips and analysis on achieving launch excellence in challenging pharma markets. Sponsored by: Outer Edge Technology With FDA approval imminent, start-up Life Sciences company partners with an industry focused MSP to design and manage its regulated cloud-based infrastructure to speed time to market. Sponsored by: DeciBio Consulting With the liquid biopsy market maturing and >80 companies still competing with liquid biopsy offerings, it is crucial for investors to be able to cut through the noise and identify the winners. Presented by: Veeva Share your thoughts on the life sciences industry's progress in improving study execution. Sponsored by: Biotech Primer The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry. BIO Asia International Conference March 5-6, 2019 | Grand Hyatt Tokyo | Tokyo, Japan PEGS: The Essential Protein Engineering Summit April 8 – 12, 2019 | Boston, MA Middle East Life Sciences Compliance Training April 29, 2019 – May 2, 2019 | Dubai U.A.E. Drug Development Boot Camp® 2019 November 20-21, 2019 | Boston, MA | Register and start preparing Today! | 