Today's Rundown Amid R&D rejigs, GlaxoSmithKline axes 6 pipeline assets Lilly cuts a trio of pipeline assets, including BTK inhibitor, diabetes drug Genentech pays Xencor $120M for rights to IL-15 cancer pipeline MacroGenics’ margetuximab beats Herceptin in phase 3 Avrobio posts encouraging update for Fabry gene therapy phase 1, 2 trials Slack telegraphs moves into healthcare as it gears up for IPO: report Featured Story | | | Wednesday, February 6, 2019 GlaxoSmithKline is cutting a host of unwanted investigational drugs as it joins other Big Pharmas in the fourth-quarter clearout. |
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Top Stories Wednesday, February 6, 2019 The Big Pharma has culled a pair of phase 2 assets—a dual amylin calcitonin receptor agonist for the treatment of diabetes and a BTK inhibitor being investigated in immunology—as well as a urocortin-2 peptide treatment for heart failure that had reached phase 1. Wednesday, February 6, 2019 Genentech has paid $120 million upfront to secure global rights to IL-15 cytokine therapeutics in preclinical development at Xencor. The upfront sets the Roche subsidiary up to incorporate the candidates into its immuno-oncology combination strategy. Wednesday, February 6, 2019 A phase 3 trial of MacroGenics’ margetuximab in HER2-positive metastatic breast cancer patients has met its primary endpoint. The anti-HER2 antibody improved progression-free survival by more than Herceptin, teeing MacroGenics up to file for approval in the second half of the year. Wednesday, February 6, 2019 The Cambridge, Massachusetts-based biotech announced updated data on Wednesday for two trials of its lentiviral-based, ex vivo gene therapy in patients who had previously received enzyme replacement therapy and patients who hadn't. Wednesday, February 6, 2019 The ubiquitous messaging company Slack has confidentially filed for an IPO—except not-so-confidentially, as it went public with the news on its own earlier this week with a press release. | This week's sponsor is Camargo. | | | [Webinar] Maximizing the Value of Your Drug Development Program
Thursday, February 21 | 11am ET / 8am PT
This webinar will benefit executives at Biotech and Pharmaceutical companies interested in learning more about 505(b)(2) drug development and how to save time and money while maximizing the value of their drug development program. Register Now! |
Enrollment Showcase | | | Sponsored by: Drexel University Online Drexel University’s online graduate programs in biomedicine, clinical research, drug discovery, and molecular medicine were developed with working professionals in mind, providing you with the education, practical skills, and competitive edge you need to be successful in your career. Learn more. |
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