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January 29, 2019

Today's Rundown

Featured Story

Neurocrine pays Voyager $165M for neurological gene therapies

Neurocrine Biosciences is set to pay Voyager Therapeutics $165 million upfront for the rights to a clutch of gene therapies. The deal sees Neurocrine commit to $1.7 billion in milestones in return for Parkinson’s disease program VY-AADC and other assets.

Top Stories

Celgene inks $1B deal for a preclinical epigenetic blood cancer drug from Canada

Celgene has signed on to a deal worth about $1 billion for a Canadian preclinical asset: a first-in-class small molecule that targets protein-protein interactions and epigenetic regulation in leukemia and lymphoma.

Pfizer/Lilly NGF pain drug wins again, but safety concern won’t go away

Pfizer and Lilly now have two pivotal trials showing NGF blocker tanezumab reduces pain in arthritis, but cases of rapid joint damage are still seen, this time including osteonecrosis.

Aldeyra boosts eye disease pipeline with $10M Helio Vision buy

Aldeyra Therapeutics is acquiring Helio Vision for $10 million upfront, adding a retinal disease drug to its pipeline. The candidate, developed for the treatment of proliferative vitreoretinopathy, should head into the clinic this year, with data to come in 2020.

Langer’s Lyndra Therapeutics bags $55M to advance ‘ultralong-acting’ pill

Lyndra Therapeutics has raised a $55 million series B round to expand its early-stage pipeline of “ultralong-acting” medicines, boost manufacturing and carry out a phase 2 trial of a long-acting pill for the treatment of schizophrenia.

Takeda-backed Maverick promotes R&D staff for T-cell push

T-cell startup Maverick Therapeutics has promoted Robert DuBridge and Chad May. The executives, who have been at Maverick since its inception, are stepping into new roles in the biotech’s R&D team.

Takeda’s dengue shot, rival to Sanofi's Dengvaxia, hits the mark in massive phase 3 study

It’s no secret Sanofi has had trouble with its world-first dengue vaccine, Dengvaxia, but that hasn't dissuaded Takeda. Its own dengue shot met its goal in a pivotal phase 3 study that covered eight countries and more than 20,000 participants.

Novartis: Alternative payments will ‘reset the paradigm’ for covering gene, cell therapies

Novartis is pleased that drug-cost watchdog ICER called its spinal muscular atrophy gene therapy cost-effective even if priced at $2 million, an executive said during a FierceBiotech discussion this week. But as costly gene and cell therapies proliferate, biopharma will have to work with insurers on alternative payment models, the panelists agreed.

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[Infographic] Clinical Development Trends And The Impact On Clinical Trial Technology

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[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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