| | Finding the right patients for a particular clinical trial involves precision, timeliness and is one of the most important hurdles to successful clinical development. Learn more about early indicators of efficacy and more from a free white paper by TD2. |
Secretive Sana, still a year away from the clinic, files for an IPO after a mammoth raise Meet Binney Street Capital: Dana-Farber Cancer Institute's first venture fund JPM: Can we take J.P. Morgan out of San Francisco? We're virtually there NewAmsterdam bags $196M to resurrect Amgen's discarded CETP drug Knopp’s oral asthma drug hits primary endpoint in phase 2 Fierce JPM Week: Koller on what 2021 holds for insitro, machine learning and working virtually Cognito Therapeutics nets FDA breakthrough label for light, sound therapy for Alzheimer's disease Eye stem cell transplant to treat blindness bolsters retinal function in monkeys Featured Story | By Ben Adams Sana Biotechnology is following the Moderna playbook to a tee: Promise a lot based on very early science, be vague, nab a major VC raise, then gun for an IPO. read more |
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| Thank you to Catalent for sponsoring this year's JPM 2021 coverage. |
Top Stories By Ben Adams The Dana-Farber Cancer Institute is getting into the life science funding biz with the launch of its venture arm Binney Street Capital. read more By Amirah Al Idrus This week's virtual J.P. Morgan Healthcare Conference gave us a rest from the behemoth the meeting has evolved into. Could it be the catalyst that gets it out of San Francisco? Reviews are mixed. Some think branding and history will keep it in town, while others thing moving the meeting won't solve its problems. read more By Nick Paul Taylor NewAmsterdam Pharma has raised $196 million to fund late-phase trials of a cardiovascular disease drug discarded by Amgen. The series A will support the revitalization of obicetrapib, part of the once-hyped CETP class of molecules that was torpedoed by a series of clinical setbacks. read more By Nick Paul Taylor A phase 2 clinical trial of Knopp Biosciences’ dexpramipexole in patients with moderate-to-severe eosinophilic asthma has met its primary endpoint. Knopp said the data support further development of a drug it is pitching as an oral alternative to antibodies such as Regeneron and Sanofi’s Dupixent. read more By Conor Hale While 2020 has changed the way we live, the pandemic may also deliver lasting changes to how we work—and, as machine learning aims to have a larger impact on the life sciences, they may be changes for the better, according to insitro founder and CEO Daphne Koller. read more By Conor Hale Using specific frequencies of flashing lights and sounds to stimulate the brain’s electrical activity, Cognito Therapeutics believes it can help treat Alzheimer’s disease by energizing neurons and reactivating the immune system. read more By Angus Liu Retinal cell transplants are considered to be an attractive approach for treating blindness. Question is, where do you source the cells? An international research team is using a type of stem cell in the eye to grow the pigmented layer of retina that’s essential for vision, and the approach is showing promise in preclinical studies. read more Resources Sponsored By: Polpharma Biologics Innovative cell lines and early process development are critical to generate a high producing cell lines alongside a USP strategy to meet high quality standards. Sponsored By: Blue Matter Biopharma companies in rare diseases: How to maximize the odds of success by becoming a valued member of the unique “rare disease ecosystem.” Sponsored by: Cytiva A one-stop hub for Cytiva resources to support process development and manufacturing of your novel molecule Sponsored by: GenScript A significant number of new treatments have been approved so far, but some manufacturing and regulatory guidelines pose challenges for advanced therapies, leading to poor production yields. Sponsored by: Catalent Cell and gene therapies hold the promise to offer novel therapeutic avenues for individuals facing serious medical conditions, but bringing them through the clinical trial process introduces a level of supply chain risk and complexity. Sponsored by: AllianceRx Walgreens Prime Gene and cell therapy are shifting paradigms for manufacturers, patients, healthcare providers and pharmacies. We invite you to learn more by reading Gene and Cell Therapy: A New Age of Medicine. Sponsored by: Catalent Autologous cell therapies have seen propelled growth since 2017, with the spotlight on the first FDA approval of a chimeric antigen receptor (CAR) T cell immunotherapy, Kymriah® (tisagenlecleucel), for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia. Sponsored by: Metabolon Learn six ways metabolomics provides greater confidence, higher success rates and complements the work of your in-house teams for your drug development pipeline. Sponsored by: Covance Download the whitepaper to learn how your safety organization can implement automation technologies to enable process and cost efficiencies, improve resource allocation and ensure compliance and quality. Sponsored By: BBK Worldwide The BBK Worldwide Study Voices 2020 survey gives voice to the healthcare consumer in the wake of COVID-19 and reveals important insights for clinical trial enrollment and engagement. Sponsored by: Premier Research Browse the latest learnings and insights from our clinical development professionals. Sponsored by: Rousselot This infographic describes the benefits of GelMA in various biomedical applications and how X-Pure® GelMA can help you in your developments. Sponsored by: Aldevron Gene and cell therapy organizations are asked to balance the need for rapid clinical progression and stringent quality expectations throughout development. In this document, Aldevron provides an in-depth look at preparing for plasmid manufacturing based on our years of experience. Sponsored By: Outer Edge Technology A sound Cloud Strategy provides the flexibility and tools businesses need to quickly adapt and operate securely in an ever-changing remote work environment. Learn how your company can cost-effectively empower its employees to be productive and secure while working remotely. Sponsored by: Catalent Learn about drug product process development challenges and risks, the difference between innovator and biosimilar drug product process development, and more during the drug product process development phase. Sponsored by: Catalent Learn about proven strategies for a successful product launch, including cross-functional team collaboration, risk management and using the right project management tools. Sponsored by: Catalent This eBook provides insights on key approaches and considerations for preparing your drug development program for long-term success. Sponsored by: Catalent In this webinar, pharmaceutical scientists present real-life examples of challenges they’ve overcome in the transfer of oral small molecules from a dedicated early-phase development site to a dedicated late-phase manufacturing site. Sponsored by: Outer Edge Technology Cybercriminals Are Actively Exploiting The Coronavirus Pandemic To Gain Entry To Enterprise Networks. Don’t Let Your Company Become The Next Ransomware Headline -- Make These Changes Now! Sponsored by: Catalent Get insights on key considerations for a successful tech transfer process for manufacturing a biologic drug product, including a case study on overcoming challenges in a process transfer for a sterile diluent. Sponsored by: Catalent In a BioPharma Dive industry survey, planning and forecasting were identified as top concerns for trial sponsors. In response to this need, the CSM team at Catalent has developed a methodology for identifying, evaluating, and proactively managing the inherent risks involved in clinical trial supply chain management. Sponsored by: Catalent Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study. Sponsored by: Catalent Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study. Sponsored by: Catalent Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study. Fierce JPM Week January 11–13, 2021, 10AM ET | Virtual Event Virtual Clinical Trials Summit February 9-10, 2021 | Virtual Event | 