Orbis raises €90M with Lilly, Novo Holdings in tow

Today’s Big News

Jan 6, 2025

Big Pharma layoff rounds jump 281% in '24, but overall industry rates similar to '23


I-Mab pauses Sanofi-partnered prospect to make play for busy CLDN18.2 space


Fierce Biotech Fundraising Tracker '25: Orbis rings in new year with €90M series A


Portage packages Tarus' adenosine receptor antagonists into new company with original leader


Oculis' peptidomimetic helps protect eyes from optic nerve inflammation in phase 2


After Xeno's gastric-bypass alternative failed, LPOXY will test pill for C. diff infection


Basecamp Research pushes for programmable genetic medicines with new computer cluster, CSO and Massachusetts lab

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Featured

Big Pharma layoff rounds jump 281% in '24, but overall industry rates similar to '23

Overall, biopharma layoffs rose ever so slightly in 2024 compared to the year before, though the number of layoff rounds across Big Pharma companies skyrocketed by 281%.
 

Top Stories

I-Mab pauses Sanofi-partnered prospect to make play for busy CLDN18.2 space

I-Mab has begun the new year with a pipeline pivot, pausing work on an asset Sanofi bought into last year to focus on its play for the congested CLDN18.2 space.

Fierce Biotech Fundraising Tracker '25: Orbis rings in new year with €90M series A

The Fierce Biotech Fundraising Tracker records venture capital rounds of $50 million or more secured by biotechs.

Discover Astellas’ differentiated approach to innovation partnerships

Discover how Astellas builds innovation partnerships with ambitious organizations that share their vision to transform the lives of patients

Portage packages Tarus' adenosine receptor antagonists into new company with original leader

More than two years after acquiring Tarus Therapeutics, Portage Biotech is relaunching Tarus’ adenosine receptor antagonists in a standalone company helmed by a familiar leader.

Oculis' peptidomimetic helps protect eyes from optic nerve inflammation in phase 2

Oculis’ peptidomimetic small molecule has been shown to help protect the eyes of patients with inflammation of the optic nerve in a phase 2 study.

After Xeno's gastric-bypass alternative failed, LPOXY will test pill for C. diff infection

Xeno Biosciences may have been unable to prove that its drug delivering oxygen to the gastrointestinal tract can induce weight loss, but LPOXY Therapeutics has penned a $7.5 million biobucks deal to see whether the candidate can deliver the goods in Clostridioides difficile.

Basecamp Research pushes for programmable genetic medicines with new computer cluster, CSO and Massachusetts lab

British tech firm Basecamp Research is making a big push forward to further its mission of developing programmable genetic medicines. The company has hired gene therapy vet John Finn, Ph.D., to be its new chief scientific officer, working out of a new office and lab space in Cambridge, Massachusetts.

FDA issues draft guidance on ensuring pulse oximeter accuracy across skin tones

The FDA has published a set of long-awaited recommendations to the industry to help ensure pulse oximeters work correctly across all skin tones.

Roche projected to claim pharma's 2025 sales crown as Novo, Lilly climb rankings: Evaluate

Even as Novo and Lilly continue to climb, Roche looks poised to remain the top drugmaker by revenue in 2025, Evaluate analysts predict.

Aetna sues drugmakers for widespread price-fixing and collusion

Mimicking prior federal and state investigations into drug manufacturers, health insurer Aetna is suing in Connecticut for rigging the generic drug market.
 
Fierce podcasts

Don’t miss an episode

Fierce 50 honorees look ahead: AI, rural health, antibiotic resistance, maternal care and more

This week on "The Top Line," we bring you a special conversation from earlier this month at our New York City gala, where we celebrated this year’s Fierce 50 honorees.
 

Resources

Whitepaper

Communicating the Value of Biopharma Assets to Potential Investors

How can an emerging company attract the right partner for a therapeutic asset (& optimize its value in a transaction)? This paper offers some insights.

 

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